Myo-inositol Supplementation to Prevent Pregnancy Complications in Polycystic Ovary Syndrome: A Randomized Clinical Trial.

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Title: Myo-inositol Supplementation to Prevent Pregnancy Complications in Polycystic Ovary Syndrome: A Randomized Clinical Trial.
Authors: van der Wel AWT; Department of Obstetrics and Gynecology, Amsterdam University Medical Center location AMC, Amsterdam, the Netherlands.; Amsterdam Reproduction & Development Research Institute, Amsterdam, the Netherlands., Frank CMC; Department of Obstetrics and Gynecology, University Medical Center Utrecht, Utrecht, the Netherlands., Bout-Rebel R; Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Erasmus University Medical Center, Rotterdam, the Netherlands., Duijnhoven RG; Department of Obstetrics and Gynecology, Amsterdam University Medical Center location AMC, Amsterdam, the Netherlands.; Clinical Trials Unit of the Netherlands Society for Obstetrics and Gynaecology, Amsterdam, the Netherlands., van Bree BE; Department of Obstetrics and Gynecology, Maastricht University Medical Centre, Maastricht, the Netherlands., Valkenburg O; Department of Obstetrics and Gynecology, Maastricht University Medical Centre, Maastricht, the Netherlands., Al-Nasiry S; Department of Obstetrics and Gynecology, Maastricht University Medical Centre, Maastricht, the Netherlands., van Oppenraaij RHF; Department of Obstetrics and Gynecology, Maasstad Hospital, Rotterdam, the Netherlands., Vogelvang TE; Department of Obstetrics and Gynecology, Diakonessenhuis Utrecht, Utrecht, the Netherlands., Westerhuis MEMH; Department of Obstetrics and Gynecology, Catharina Hospital, Eindhoven, the Netherlands., van de Nieuwenhof HP; Department of Obstetrics and Gynecology, Jeroen Bosch Hospital, 's-Hertogenbosch, the Netherlands., Gielen SCJP; Department of Obstetrics and Gynecology, Franciscus Gasthuis and Vlietland, Rotterdam, the Netherlands., Bandell ML; Department of Obstetrics and Gynecology, Albert Schweitzer Hospital, Dordrecht, the Netherlands., Bekker MN; Department of Obstetrics and Gynecology, University Medical Center Utrecht, Utrecht, the Netherlands., Wouters MGAJ; Department of Obstetrics and Gynecology, Amsterdam University Medical Center location AMC, Amsterdam, the Netherlands.; Amsterdam Reproduction & Development Research Institute, Amsterdam, the Netherlands., Mijatovic V; Amsterdam Reproduction & Development Research Institute, Amsterdam, the Netherlands.; Department of Reproductive Medicine, Amsterdam University Medical Center location AMC, Amsterdam, the Netherlands., Franx A; Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Erasmus University Medical Center, Rotterdam, the Netherlands., Lambalk CB; Amsterdam Reproduction & Development Research Institute, Amsterdam, the Netherlands.; Department of Reproductive Medicine, Amsterdam University Medical Center location AMC, Amsterdam, the Netherlands., Broekmans FJM; Department of Reproductive Medicine and Gynecology, University Medical Center Utrecht & University of Utrecht, Utrecht, the Netherlands.; Centre for Reproductive Medicine, Dijklander Ziekenhuis, Purmerend, the Netherlands., de Weerd S; Department of Obstetrics and Gynecology, Albert Schweitzer Hospital, Dordrecht, the Netherlands., Gerards JMH; Department of Obstetrics and Gynecology, Diakonessenhuis Utrecht, Utrecht, the Netherlands., Baalman JH; Department of Obstetrics and Gynecology, Medisch Spectrum Twente, Enschede, the Netherlands., van Disseldorp J; Department of Obstetrics and Gynecology, Sint Antonius Hospital, Nieuwegein, the Netherlands., Langenveld J; Department of Obstetrics and Gynecology, Zuyderland MC, Heerlen, the Netherlands., Gunning MN; Department of Reproductive Medicine and Gynecology, University Medical Center Utrecht & University of Utrecht, Utrecht, the Netherlands., Frederix GWJ; Department of Public Health, Julius Center Research Program Methodology, University Medical Centre Utrecht, Utrecht, the Netherlands., Painter RC; Amsterdam Reproduction & Development Research Institute, Amsterdam, the Netherlands.; Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Erasmus University Medical Center, Rotterdam, the Netherlands., Fauser BCJM; Department of Reproductive Medicine and Gynecology, University Medical Center Utrecht & University of Utrecht, Utrecht, the Netherlands., Laven JSE; Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Erasmus University Medical Center, Rotterdam, the Netherlands., van Rijn BB; Department of Obstetrics and Gynecology, Máxima Medical Center, Veldhoven, the Netherlands.; Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, the Netherlands.
Source: JAMA [JAMA] 2025 Oct 07; Vol. 334 (13), pp. 1151-1159.
Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 7501160 Publication Model: Print Cited Medium: Internet ISSN: 1538-3598 (Electronic) Linking ISSN: 00987484 NLM ISO Abbreviation: JAMA Subsets: MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:1538-3598
DOI:10.1001/jama.2025.13668