Pain, Agitation, Delirium, and Iatrogenic Withdrawal Syndrome Management in Children Who Are Critically Ill: Protocol for a European Clinical Practice Guideline Using the Grading of Recommendations Assessment, Development, and Evaluation Approach.

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Title: Pain, Agitation, Delirium, and Iatrogenic Withdrawal Syndrome Management in Children Who Are Critically Ill: Protocol for a European Clinical Practice Guideline Using the Grading of Recommendations Assessment, Development, and Evaluation Approach.
Authors: MacDonald I; Institute of Higher Education and Research in Healthcare, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland., Cavin-Trombert A; Medical Library, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Jaques C; Medical Library, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., De Clifford-Faugère G; Institute of Higher Education and Research in Healthcare, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland., De Cock PA; Department of Pharmacy, Ghent University Hospital, Ghent, Belgium.; Department of Basic and Applied Health Sciences, Ghent University, Ghent, Belgium.; Department of Pediatric Intensive Care, Ghent University Hospital, Ghent, Belgium., de Wildt SN; Department of Pharmacy, Pharmacology and Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Neonatal and Pediatric Intensive Care - Pediatric Intensive Care, Erasmus MC - Sophia Children's Hospital, Erasmus University Medical Center, Rotterdam, The Netherlands., Dmytriiev D; Department of Anesthesiology and Intensive Care, Vinnitsya National Medical University, Vinnitsya, Ukraine., Engel J; Intensive Care Medicine and Pulmonology, Department of Cardiology, University Children's Hospital Tuebingen, Tuebingen, Germany., Fazio PC; Pediatric Intensive Care Unit, University-Hospital of Padua, Padua, Italy., George S; Paediatric Critical Care Unit & Department of Pharmacy, Oxford University NHS Foundation Trust, Oxford, United Kingdom., Goyer I; Department of Pharmacy, Pediatrics, Anaesthesia and Critical Care, University Hospital of Caen, Caen, France., Harðardóttir A; Intensive Care Unit, National University Hospital of Iceland, Reykjavík, Iceland., Harris J; Division of Children's Nursing, London South Bank University, London, United Kingdom., Horváth K; Pediatric Center, Semmelweis University, Budapest, Hungary., Ista E; Department of Neonatal and Pediatric Intensive Care - Pediatric Intensive Care, Erasmus MC - Sophia Children's Hospital, Erasmus University Medical Center, Rotterdam, The Netherlands.; Section Nursing Science, Department of Internal Medicine, Erasmus MC, Erasmus University Medical Center, Rotterdam, The Netherlands., Mencía S; Pediatric Intensive Care Unit, Gregorio Marañón Hospital, Complutense University of Madrid, Madrid, Spain., Metsvaht T; Institute of Clinical Medicine, Department of Paediatrics, University of Tartu, Tartu, Estonia.; Paediatric and Neonatal Intensive Care Unit, Tartu University Hospital, Tartu, Estonia., Mondardini MC; Pediatric Anesthesia and Intensive Care Unit, Department of Woman's and Child's Health, IRCCS AOUBO, Bologna, Italy., Oualha M; Pediatric Intensive Care Unit, Necker University Hospital, Paris, France.; Paris City University, Paris, France., Perez MH; Paediatric Intensive and Intermediate Care Units, Service of Pediatrics, Women-Mother-Child Department, Lausanne University Hospital, Lausanne, Switzerland.; Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland., Pietrzkiewicz K; Department of Paediatric Anaesthesiology and Intensive Therapy, Poznan University of Medical Sciences, Poznan, Poland., Sperotto F; Department of Cardiology, Boston Children's Hospital, Boston, MA, United States.; Department of Pediatrics, Harvard Medical School, Boston, MA, United States., Wyness B; Pharmacy Department, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom., Yalındağ N; School of Medicine, Marmara University, Istanbul, Turkey.; Division of Pediatric Critical Care, Department of Pediatrics, Marmara University Pendik Training and Research Hospital, Istanbul, Turkey., Amigoni A; Pediatric Intensive Care unit, University Hospital of Padova, Padova, Italy., Ramelet AS; Institute of Higher Education and Research in Healthcare, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.; Paediatric Intensive and Intermediate Care Units, Service of Pediatrics, Women-Mother-Child Department, Lausanne University Hospital, Lausanne, Switzerland.
Corporate Authors: ESPNIC Nursing and Allied Healthcare Professionals Section; See Acknowledgments, ESPNIC Pharmacology Section; See Acknowledgments
Source: JMIR research protocols [JMIR Res Protoc] 2025 Sep 08; Vol. 14, pp. e67930. Date of Electronic Publication: 2025 Sep 08.
Publication Type: Journal Article
Journal Info: Publisher: JMIR Publications Country of Publication: Canada NLM ID: 101599504 Publication Model: Electronic Cited Medium: Internet ISSN: 1929-0748 (Electronic) Linking ISSN: 19290748 NLM ISO Abbreviation: JMIR Res Protoc Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1929-0748
DOI:10.2196/67930