Expression of intron-containing HIV-1 RNA induces NLRP1 inflammasome activation in myeloid cells.

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Title: Expression of intron-containing HIV-1 RNA induces NLRP1 inflammasome activation in myeloid cells.
Authors: Jalloh S; Department of Virology, Immunology & Microbiology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, United States of America., Hughes IK; Department of Virology, Immunology & Microbiology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, United States of America., Akiyama H; Department of Virology, Immunology & Microbiology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, United States of America., Gojanovich AD; Center for Regenerative Medicine (CReM), Boston University Chobanian & Avedisian School of Medicine and Boston Medical Center, Boston, Massachusetts, United States of America., Quiñones-Molina AA; Department of Virology, Immunology & Microbiology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, United States of America., Yang M; Center for Regenerative Medicine (CReM), Boston University Chobanian & Avedisian School of Medicine and Boston Medical Center, Boston, Massachusetts, United States of America., Henderson AJ; Department of Virology, Immunology & Microbiology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, United States of America.; Department of Medicine, Section of Infectious Diseases, Boston Medical Center, Boston, Massachusetts, United States of America., Mostoslavsky G; Department of Virology, Immunology & Microbiology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, United States of America.; Center for Regenerative Medicine (CReM), Boston University Chobanian & Avedisian School of Medicine and Boston Medical Center, Boston, Massachusetts, United States of America., Gummuluru S; Department of Virology, Immunology & Microbiology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, United States of America.
Source: PLoS biology [PLoS Biol] 2025 Sep 08; Vol. 23 (9), pp. e3003320. Date of Electronic Publication: 2025 Sep 08 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet ISSN: 1545-7885 (Electronic) Linking ISSN: 15449173 NLM ISO Abbreviation: PLoS Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1545-7885
DOI:10.1371/journal.pbio.3003320