Accelerated T-cell senescence and persistent inflammation in older adults with rheumatoid arthritis.

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Title: Accelerated T-cell senescence and persistent inflammation in older adults with rheumatoid arthritis.
Authors: Cezar CD; Laboratory of Immunobiology, School of Health and Life Sciences, Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre, Brazil., Scholl JN; Laboratory of Immunobiology, School of Health and Life Sciences, Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre, Brazil; National Institute of Science and Technology - Neuroimmunomodulation (INCT-NIM), Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), Brasília, Brazil., Rabelo CF; Rheumatology Unit, Hospital São Lucas da PUCRS, Porto Alegre, Brazil., Madruga MP; Laboratory of Immunobiology, School of Health and Life Sciences, Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre, Brazil., da Silva PL; Laboratory of Immunobiology, School of Health and Life Sciences, Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre, Brazil., Grun LK; Laboratory of Immunobiology, School of Health and Life Sciences, Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre, Brazil; Graduate Program in Pediatrics and Child Health, School of Medicine, Pontifical Catholic University at Rio Grande do Sul (PUCRS), Porto Alegre, Brazil., Engroff P; Institute of Geriatrics and Gerontology, PUCRS, Porto Alegre, Brazil., Bressanim ACM; Institute of Geriatrics and Gerontology, PUCRS, Porto Alegre, Brazil., Scherer RT; Institute of Geriatrics and Gerontology, PUCRS, Porto Alegre, Brazil., Schwanke CHA; Institute of Geriatrics and Gerontology, PUCRS, Porto Alegre, Brazil; Graduate Programe in Biomedical Gerontology, School of Medicine, PUCRS, Porto Alegre, Brazil., Barbé-Tuana F; Laboratory of Immunobiology, School of Health and Life Sciences, Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre, Brazil; Graduate Program in Pediatrics and Child Health, School of Medicine, Pontifical Catholic University at Rio Grande do Sul (PUCRS), Porto Alegre, Brazil., Sato DK; Institute of Geriatrics and Gerontology, PUCRS, Porto Alegre, Brazil; Instituto do Cérebro do Rio Grande do Sul (InsCer), PUCRS, Porto Alegre, Brazil., Bauer ME; Laboratory of Immunobiology, School of Health and Life Sciences, Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre, Brazil; Graduate Programe in Biomedical Gerontology, School of Medicine, PUCRS, Porto Alegre, Brazil; National Institute of Science and Technology - Neuroimmunomodulation (INCT-NIM), Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), Brasília, Brazil. Electronic address: mebauer@pucrs.br.
Source: International immunopharmacology [Int Immunopharmacol] 2025 Nov 14; Vol. 165, pp. 115518. Date of Electronic Publication: 2025 Sep 08.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1878-1705
DOI:10.1016/j.intimp.2025.115518