Loop Diuretic Dose Intensification versus Adjuvant Thiazide for Diuretic Resistance in Acute Heart Failure: Mechanistic Randomized Controlled Trial.

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Bibliographic Details
Title: Loop Diuretic Dose Intensification versus Adjuvant Thiazide for Diuretic Resistance in Acute Heart Failure: Mechanistic Randomized Controlled Trial.
Authors: Rao VS; Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut., Cox ZL; Department of Pharmacy Practice, Lipscomb University College of Pharmacy, Nashville, Tennessee.; Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee., Ivey-Miranda JB; Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.; Hospital de Cardiologia, Instituto Mexicano del Seguro Social, Mexico City, Mexico., Moreno-Villagomez J; Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.; Facultad de Estudios Superiores Iztacala, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico., Ramos-Mastache D; Facultad de Estudios Superiores Iztacala, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico., Maulion C; Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut., Bellumkonda L; Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut., Turner J; Section of Nephrology, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut., Wilson FP; Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.; Clinical and Translational Research Accelerator, Yale University School of Medicine, New Haven, Connecticut., Shilpak MG; Kidney Health Research Collaborative, Department of Medicine, University of California San Francisco, San Francisco, California., Estrella MM; Kidney Health Research Collaborative, Department of Medicine, University of California San Francisco, San Francisco, California., Welling P; Departments of Medicine and Physiology, John Hopkins School of Medicine, Baltimore, Maryland., Wilcox CS; Division of Nephrology and Hypertension Center, Georgetown University, Washington, DC., Ellison DH; Oregon Clinical and Translational Research Institute, Oregon Health and Science University, Portland, Oregon., Forbush B; Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut., Testani JM; Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.
Source: Journal of the American Society of Nephrology : JASN [J Am Soc Nephrol] 2026 Mar 01; Vol. 37 (3), pp. 533-544. Date of Electronic Publication: 2025 Sep 12.
Publication Type: Journal Article
Journal Info: Publisher: Wolters Kluwer Health, on behalf of the American Society of Nephrology Country of Publication: United States NLM ID: 9013836 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1533-3450 (Electronic) Linking ISSN: 10466673 NLM ISO Abbreviation: J Am Soc Nephrol Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
Description
ISSN:1533-3450
DOI:10.1681/ASN.0000000887