Methylglyoxal Aggregates α-Synuclein by Inhibiting SIRT1-Hif-1α in Intestinal Enteroendocrine Cells.

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Title: Methylglyoxal Aggregates α-Synuclein by Inhibiting SIRT1-Hif-1α in Intestinal Enteroendocrine Cells.
Authors: Huh E; Department of Oriental Pharmaceutical Science, College of Pharmacy, Kyung Hee University, Seoul, Republic of Korea.; Department of Formulae Pharmacology, College of Korean Medicine, Gachon University, Seongnam-si, Republic of Korea., Kim JM; Department of Formulae Pharmacology, College of Korean Medicine, Gachon University, Seongnam-si, Republic of Korea., Kim SH; Department of Formulae Pharmacology, College of Korean Medicine, Gachon University, Seongnam-si, Republic of Korea., Choi Y; Department of Biochemical and Pharmaceutical Sciences, Graduate School, Kyung Hee University, Seoul, Republic of Korea., Park MG; MetaCen Therapeutics Inc. R&D Center, Suwon-si, Republic of Korea., Oh MS; Department of Oriental Pharmaceutical Science, College of Pharmacy, Kyung Hee University, Seoul, Republic of Korea.; Department of Biochemical and Pharmaceutical Sciences, Graduate School, Kyung Hee University, Seoul, Republic of Korea.
Source: International journal of toxicology [Int J Toxicol] 2026 Jan-Feb; Vol. 45 (1), pp. 22-28. Date of Electronic Publication: 2025 Sep 13.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Sage Publications Country of Publication: United States NLM ID: 9708436 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1092-874X (Electronic) Linking ISSN: 10915818 NLM ISO Abbreviation: Int J Toxicol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1092-874X
DOI:10.1177/10915818251378724