Combined agonism of nutrient receptors GPR40 and GPR119 with K-757 and K-833 results in weight loss and blood pressure reductions in obese subjects without type 2 diabetes mellitus.

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Title: Combined agonism of nutrient receptors GPR40 and GPR119 with K-757 and K-833 results in weight loss and blood pressure reductions in obese subjects without type 2 diabetes mellitus.
Authors: Crutchlow M; Kallyope, Inc., New York, New York, USA., Liu J; Kallyope, Inc., New York, New York, USA., Romero C; Headlands Research, Brownsville, Texas, USA., Watkins E; ProSciento, Chula Vista, California, USA., Zhang H; Kallyope, Inc., New York, New York, USA., Arreglado A; Kallyope, Inc., New York, New York, USA., Vance A; Kallyope, Inc., New York, New York, USA., Boisvert D; Kallyope, Inc., New York, New York, USA., Terracina G; Kallyope, Inc., New York, New York, USA., Chan B; Kallyope, Inc., New York, New York, USA., Consolati MJ; Kallyope, Inc., New York, New York, USA., Poterewicz G; Kallyope, Inc., New York, New York, USA., Talaty JE; BCH Research Solutions, LLC, Conshohocken, Pennsylvania, USA., Lauring B; Kallyope, Inc., New York, New York, USA.
Source: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2025 Dec; Vol. 27 (12), pp. 7198-7209. Date of Electronic Publication: 2025 Sep 15.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase I; Clinical Trial, Phase II
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100883645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-1326 (Electronic) Linking ISSN: 14628902 NLM ISO Abbreviation: Diabetes Obes Metab Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1463-1326
DOI:10.1111/dom.70120