Tiprelestat for treatment of hospitalized COVID-19: results of the double-blind randomized placebo-controlled COMCOVID trial.

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Title: Tiprelestat for treatment of hospitalized COVID-19: results of the double-blind randomized placebo-controlled COMCOVID trial.
Authors: Bergs I; Department of Pneumology and Intensive Care Medicine, RWTH Aachen University Hospital, Pauwelsstr. 30, 52074, Aachen, Germany. ibergs@ukaachen.de., Budweiser S; Department of Internal Medicine III, RoMed Klinikum Rosenheim, Rosenheim, Germany., Henneicke-von Zepelin HH; tiakis Biotech AG, Kiel, Germany., Kelm H; Department of Pneumology, Ruppin Hospital, Neuruppin, Germany., Bollmann T; Department of Pneumology, Helios Hospital, Stralsund, Germany., Tebbe JJ; Department of Gastroenterology and Infectiology, Hospital Lippe, Medical School and University Medical Center OWL, Bielefeld University, Bielefeld, Germany., Sorichter S; Department of Pneumology and Respiratory Medicine, St. Josefskrankenhaus, Freiburg i.B., Germany., Lüth S; Department of Internal Medicine II, University Hospital, Brandenburg an der Havel, Germany., Walterspacher S; Department Department of Pneumology, Medical Clinic, Hospital of Konstanz, Constance, Germany, and Witten/Herdecke University, Witten, Germany., Wege H; Department of General Internal Medicine, Oncology/Haematology, Gastroenterology and Infectiology, Hospital Esslingen, Esslingen, Germany., Wiedow O; tiakis Biotech AG, Kiel, Germany., Dreher M; Department of Pneumology and Intensive Care Medicine, RWTH Aachen University Hospital, Pauwelsstr. 30, 52074, Aachen, Germany.
Source: Advances in therapy [Adv Ther] 2025 Nov; Vol. 42 (11), pp. 5683-5695. Date of Electronic Publication: 2025 Sep 16.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study
Journal Info: Publisher: Health Communications Inc Country of Publication: United States NLM ID: 8611864 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1865-8652 (Electronic) Linking ISSN: 0741238X NLM ISO Abbreviation: Adv Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1865-8652
DOI:10.1007/s12325-025-03362-w