Single-cell RNA sequencing and proteomics uncover SIRPα-CD47 immune checkpoint and glycolysis-driven immune evasion in cardiac myxoma.
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| Title: | Single-cell RNA sequencing and proteomics uncover SIRPα-CD47 immune checkpoint and glycolysis-driven immune evasion in cardiac myxoma. |
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| Authors: | Zhu X; Department of Cardiovascular Surgery, The Fifth Central Hospital of Tianjin, Tianjin, China.; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China.; Tianjin Pharmaceutical Research Institute Co., LTD, Tianjin, China., Gao Q; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China., Dai X; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China., Sun B; State Key Laboratory of Medicinal Chemical Biology, College of Life Science, Nankai University, Tianjin, China., Li Y; Department of Pathology and Institute of Precision Medicine, Jining Medical University, Jining, China., Zhai H; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China.; Tianjin Pharmaceutical Research Institute Co., LTD, Tianjin, China.; Department of Ultrasound, Tianjin Medical University General Hospital, Tianjin, China., Shan C; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China. |
| Source: | Frontiers in immunology [Front Immunol] 2025 Sep 01; Vol. 16, pp. 1652645. Date of Electronic Publication: 2025 Sep 01 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1664-3224 |
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| DOI: | 10.3389/fimmu.2025.1652645 |
