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Maternal inheritance suppresses CAA and amyloid plaques in 5xFAD (Tg7031)/APOE4 mice.

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Title: Maternal inheritance suppresses CAA and amyloid plaques in 5xFAD (Tg7031)/APOE4 mice.
Authors: Saadi F; Department of Neurology, Hope Center for Neurological Disorders, Washington University School of Medicine, 660 S. Euclid Avenue, St. Louis, MO 63110, USA; Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University School of Medicine, 4488 Forest Park Avenue, St. Louis, MO 63108, USA., Katritch IV; Department of Neurology, Hope Center for Neurological Disorders, Washington University School of Medicine, 660 S. Euclid Avenue, St. Louis, MO 63110, USA; Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University School of Medicine, 4488 Forest Park Avenue, St. Louis, MO 63108, USA., Parhizkar S; Department of Neurology, Hope Center for Neurological Disorders, Washington University School of Medicine, 660 S. Euclid Avenue, St. Louis, MO 63110, USA; Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University School of Medicine, 4488 Forest Park Avenue, St. Louis, MO 63108, USA., Lugo B; Department of Neurology, Hope Center for Neurological Disorders, Washington University School of Medicine, 660 S. Euclid Avenue, St. Louis, MO 63110, USA., Cho Y; Department of Neurology, Hope Center for Neurological Disorders, Washington University School of Medicine, 660 S. Euclid Avenue, St. Louis, MO 63110, USA., Ulrich JD; Department of Neurology, Hope Center for Neurological Disorders, Washington University School of Medicine, 660 S. Euclid Avenue, St. Louis, MO 63110, USA; Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University School of Medicine, 4488 Forest Park Avenue, St. Louis, MO 63108, USA., Holtzman DM; Department of Neurology, Hope Center for Neurological Disorders, Washington University School of Medicine, 660 S. Euclid Avenue, St. Louis, MO 63110, USA; Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University School of Medicine, 4488 Forest Park Avenue, St. Louis, MO 63108, USA. Electronic address: holtzman@wustl.edu.
Source: Neuron [Neuron] 2025 Sep 17; Vol. 113 (18), pp. 2883-2884.
Publication Type: Letter
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 8809320 Publication Model: Print Cited Medium: Internet ISSN: 1097-4199 (Electronic) Linking ISSN: 08966273 NLM ISO Abbreviation: Neuron Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
Description
ISSN:1097-4199
DOI:10.1016/j.neuron.2025.08.008