Spindle-localized F-actin regulates polar MTOC organization and the fidelity of meiotic spindle formation.

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Title: Spindle-localized F-actin regulates polar MTOC organization and the fidelity of meiotic spindle formation.
Authors: Soto-Moreno EJ; Division of Animal Sciences, University of Missouri, Columbia, MO, USA., Ali NN; Division of Animal Sciences, University of Missouri, Columbia, MO, USA., Küllmer F; Friedrich-Schiller-Universität (FSU), Institut für Organische Chemie und Makromolekulare Chemie, Jena, Germany., Nasufovic V; Friedrich-Schiller-Universität (FSU), Institut für Organische Chemie und Makromolekulare Chemie, Jena, Germany., Frolikova M; Laboratory of Reproductive Biology, Institute of Biotechnology of the Czech Academy of Sciences, BIOCEV, Vestec, Czech Republic., Tepla O; Laboratory of Reproductive Biology, Institute of Biotechnology of the Czech Academy of Sciences, BIOCEV, Vestec, Czech Republic.; Department of Gynaecology, Obstetrics and Neonatology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic., Masata J; Department of Gynaecology, Obstetrics and Neonatology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic., Trauner D; Department of Chemistry, University of Pennsylvania, Philadelphia, PA, USA., Patterson AA; Division of Animal Sciences, University of Missouri, Columbia, MO, USA., Arndt HD; Friedrich-Schiller-Universität (FSU), Institut für Organische Chemie und Makromolekulare Chemie, Jena, Germany., Komrskova K; Laboratory of Reproductive Biology, Institute of Biotechnology of the Czech Academy of Sciences, BIOCEV, Vestec, Czech Republic.; Department of Zoology, Faculty of Science, Charles University, Prague, Czech Republic., Zernicka-Goetz M; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA., Glover DM; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA., Balboula AZ; Division of Animal Sciences, University of Missouri, Columbia, MO, USA. abalboula@missouri.edu.
Source: Nature communications [Nat Commun] 2025 Sep 19; Vol. 16 (1), pp. 8323. Date of Electronic Publication: 2025 Sep 19.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-63586-w