Bioavailability enhancement and neuropharmacological effects of Dauricine under intranasal administration to improve cognitive impairment via PI3K/AKT/mTOR pathway.

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Title: Bioavailability enhancement and neuropharmacological effects of Dauricine under intranasal administration to improve cognitive impairment via PI3K/AKT/mTOR pathway.
Authors: Xie R; Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China., Liu Z; Department of Chemistry & the MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, 361005, China., Zheng J; Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China., Tan Q; Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China., Wu H; Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China., Liang Y; Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China. liangyong@gzucm.edu.cn.; Department of Chemistry & the MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, 361005, China. liangyong@gzucm.edu.cn.
Source: Drug delivery and translational research [Drug Deliv Transl Res] 2026 May; Vol. 16 (5), pp. 1607-1628. Date of Electronic Publication: 2025 Sep 19.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 101540061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2190-3948 (Electronic) Linking ISSN: 2190393X NLM ISO Abbreviation: Drug Deliv Transl Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Bioavailability enhancement and neuropharmacological effects of Dauricine under intranasal administration to improve cognitive impairment via PI3K/AKT/mTOR pathway.
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  Data: <searchLink fieldCode="AU" term="%22Xie+R%22">Xie R</searchLink>; Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.<br /><searchLink fieldCode="AU" term="%22Liu+Z%22">Liu Z</searchLink>; Department of Chemistry & the MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, 361005, China.<br /><searchLink fieldCode="AU" term="%22Zheng+J%22">Zheng J</searchLink>; Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.<br /><searchLink fieldCode="AU" term="%22Tan+Q%22">Tan Q</searchLink>; Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.<br /><searchLink fieldCode="AU" term="%22Wu+H%22">Wu H</searchLink>; Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.<br /><searchLink fieldCode="AU" term="%22Liang+Y%22">Liang Y</searchLink>; Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China. liangyong@gzucm.edu.cn.; Department of Chemistry & the MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, 361005, China. liangyong@gzucm.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101540061%22">Drug delivery and translational research</searchLink> [Drug Deliv Transl Res] 2026 May; Vol. 16 (5), pp. 1607-1628. <i>Date of Electronic Publication: </i>2025 Sep 19.
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        Value: 10.1007/s13346-025-01975-w
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      – TitleFull: Bioavailability enhancement and neuropharmacological effects of Dauricine under intranasal administration to improve cognitive impairment via PI3K/AKT/mTOR pathway.
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            NameFull: Xie R
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            NameFull: Liu Z
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              Text: 2026 May
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              Y: 2026
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