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Comparative analysis of cerebrospinal fluid neurofilament medium, light and heavy chain in neurodegenerative diseases using an in-house assay for the detection of neurofilament medium chain.

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Title: Comparative analysis of cerebrospinal fluid neurofilament medium, light and heavy chain in neurodegenerative diseases using an in-house assay for the detection of neurofilament medium chain.
Authors: Fazeli B; Department of Neurology, Ulm University Hospital, 89081, Ulm, Germany., Botzenhardt S; Department of Neurology, Ulm University Hospital, 89081, Ulm, Germany., Bachhuber F; Department of Neurology, Ulm University Hospital, 89081, Ulm, Germany., Klassen P; Department of Neurology, Ulm University Hospital, 89081, Ulm, Germany; German Centre for Neurodegenerative Diseases (DZNE e.V.), 89081, Ulm, Germany., Klose V; Department of Neurology, Ulm University Hospital, 89081, Ulm, Germany; German Centre for Neurodegenerative Diseases (DZNE e.V.), 89081, Ulm, Germany., Dorst J; Department of Neurology, Ulm University Hospital, 89081, Ulm, Germany., Wiesenfarth M; Department of Neurology, Ulm University Hospital, 89081, Ulm, Germany., Uzelac Z; Department of Neurology, Ulm University Hospital, 89081, Ulm, Germany., Jesse S; Department of Neurology, Ulm University Hospital, 89081, Ulm, Germany., Brenner D; Department of Neurology, Ulm University Hospital, 89081, Ulm, Germany., Anderl-Straub S; Department of Neurology, Ulm University Hospital, 89081, Ulm, Germany., Ludolph AC; Department of Neurology, Ulm University Hospital, 89081, Ulm, Germany., Otto M; Department of Neurology, University Hospital Halle, 06120, Halle (Saale), Germany., Weishaupt J; Department of Neurology, Ulm University Hospital, 89081, Ulm, Germany., Tumani H; Department of Neurology, Ulm University Hospital, 89081, Ulm, Germany., Halbgebauer S; Department of Neurology, Ulm University Hospital, 89081, Ulm, Germany; German Centre for Neurodegenerative Diseases (DZNE e.V.), 89081, Ulm, Germany. Electronic address: steffen.halbgebauer@uni-ulm.de.
Source: EBioMedicine [EBioMedicine] 2025 Oct; Vol. 120, pp. 105930. Date of Electronic Publication: 2025 Sep 19.
Publication Type: Journal Article; Comparative Study
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101647039 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3964 (Electronic) Linking ISSN: 23523964 NLM ISO Abbreviation: EBioMedicine Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2352-3964
DOI:10.1016/j.ebiom.2025.105930