Enhancing cardiac serine biosynthesis mitigates the progression of dilated cardiomyopathy in mice.

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Title: Enhancing cardiac serine biosynthesis mitigates the progression of dilated cardiomyopathy in mice.
Authors: Kay M; Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USA; Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA., Samuelsson AM; Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA; Department of Ophthalmology, Stanford University School of Medicine, Stanford, CA, USA., Bharucha N; Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USA; Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA., Li X; Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA; Department of Ophthalmology, Stanford University School of Medicine, Stanford, CA, USA., Ramchandani R; Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USA; Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA., Baum RE; Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USA; Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA., Ruiz Arvizo D; Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USA; Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA., Laguerre A; Salk Institute for Biological Studies, La Jolla, CA, USA., Lajevardi S; Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USA; Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA., Kambhampati S; Salk Institute for Biological Studies, La Jolla, CA, USA., Metallo CM; Salk Institute for Biological Studies, La Jolla, CA, USA., Kapiloff MS; Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA; Department of Ophthalmology, Stanford University School of Medicine, Stanford, CA, USA., Karakikes I; Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USA; Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA. Electronic address: ioannis1@stanford.edu.
Source: Metabolism: clinical and experimental [Metabolism] 2026 Jan; Vol. 174, pp. 156395. Date of Electronic Publication: 2025 Sep 18.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 0375267 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-8600 (Electronic) Linking ISSN: 00260495 NLM ISO Abbreviation: Metabolism Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1532-8600
DOI:10.1016/j.metabol.2025.156395