Telomeric DNA damage response mediates neurotoxicity of Aβ42 oligomers in Alzheimer's disease.
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| Title: | Telomeric DNA damage response mediates neurotoxicity of Aβ42 oligomers in Alzheimer's disease. |
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| Authors: | Sepe S; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy., Rey F; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy., Mancheno-Ferris A; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy., Bigi A; Department of Experimental and Clinical Biomedical Sciences, Section of Biochemistry, University of Florence, Florence, Italy., Fani G; Department of Experimental and Clinical Biomedical Sciences, Section of Biochemistry, University of Florence, Florence, Italy., Damiani D; Center for Human Technologies, Non-coding RNAs and RNA-based Therapeutics, Istituto Italiano di Tecnologia (IIT), Genova, Italy., Cabrini M; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy.; Institute of Molecular Genetics (IGM), National Research Institute (CNR), Pavia, Italy., Marinelli E; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy., Aguado J; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy.; University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Contu L; Center for Human Technologies, Non-coding RNAs and RNA-based Therapeutics, Istituto Italiano di Tecnologia (IIT), Genova, Italy., di Lillo A; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy., Boggio S; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy., Tavella S; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy.; Institute of Molecular Genetics (IGM), National Research Institute (CNR), Pavia, Italy., Rosso I; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy., Gustincich S; Center for Human Technologies, Non-coding RNAs and RNA-based Therapeutics, Istituto Italiano di Tecnologia (IIT), Genova, Italy., Chiti F; Department of Experimental and Clinical Biomedical Sciences, Section of Biochemistry, University of Florence, Florence, Italy., d'Adda di Fagagna F; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy. fabrizio.dadda@igm.cnr.it.; Institute of Molecular Genetics (IGM), National Research Institute (CNR), Pavia, Italy. fabrizio.dadda@igm.cnr.it. |
| Source: | The EMBO journal [EMBO J] 2025 Nov; Vol. 44 (21), pp. 6078-6111. Date of Electronic Publication: 2025 Sep 21. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1460-2075 |
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| DOI: | 10.1038/s44318-025-00521-1 |
