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Telomeric DNA damage response mediates neurotoxicity of Aβ42 oligomers in Alzheimer's disease.

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Title: Telomeric DNA damage response mediates neurotoxicity of Aβ42 oligomers in Alzheimer's disease.
Authors: Sepe S; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy., Rey F; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy., Mancheno-Ferris A; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy., Bigi A; Department of Experimental and Clinical Biomedical Sciences, Section of Biochemistry, University of Florence, Florence, Italy., Fani G; Department of Experimental and Clinical Biomedical Sciences, Section of Biochemistry, University of Florence, Florence, Italy., Damiani D; Center for Human Technologies, Non-coding RNAs and RNA-based Therapeutics, Istituto Italiano di Tecnologia (IIT), Genova, Italy., Cabrini M; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy.; Institute of Molecular Genetics (IGM), National Research Institute (CNR), Pavia, Italy., Marinelli E; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy., Aguado J; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy.; University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Contu L; Center for Human Technologies, Non-coding RNAs and RNA-based Therapeutics, Istituto Italiano di Tecnologia (IIT), Genova, Italy., di Lillo A; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy., Boggio S; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy., Tavella S; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy.; Institute of Molecular Genetics (IGM), National Research Institute (CNR), Pavia, Italy., Rosso I; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy., Gustincich S; Center for Human Technologies, Non-coding RNAs and RNA-based Therapeutics, Istituto Italiano di Tecnologia (IIT), Genova, Italy., Chiti F; Department of Experimental and Clinical Biomedical Sciences, Section of Biochemistry, University of Florence, Florence, Italy., d'Adda di Fagagna F; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy. fabrizio.dadda@igm.cnr.it.; Institute of Molecular Genetics (IGM), National Research Institute (CNR), Pavia, Italy. fabrizio.dadda@igm.cnr.it.
Source: The EMBO journal [EMBO J] 2025 Nov; Vol. 44 (21), pp. 6078-6111. Date of Electronic Publication: 2025 Sep 21.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Telomeric DNA damage response mediates neurotoxicity of Aβ42 oligomers in Alzheimer's disease.
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  Data: <searchLink fieldCode="AU" term="%22Sepe+S%22">Sepe S</searchLink>; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Rey+F%22">Rey F</searchLink>; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Mancheno-Ferris+A%22">Mancheno-Ferris A</searchLink>; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Bigi+A%22">Bigi A</searchLink>; Department of Experimental and Clinical Biomedical Sciences, Section of Biochemistry, University of Florence, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Fani+G%22">Fani G</searchLink>; Department of Experimental and Clinical Biomedical Sciences, Section of Biochemistry, University of Florence, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Damiani+D%22">Damiani D</searchLink>; Center for Human Technologies, Non-coding RNAs and RNA-based Therapeutics, Istituto Italiano di Tecnologia (IIT), Genova, Italy.<br /><searchLink fieldCode="AU" term="%22Cabrini+M%22">Cabrini M</searchLink>; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy.; Institute of Molecular Genetics (IGM), National Research Institute (CNR), Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Marinelli+E%22">Marinelli E</searchLink>; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Aguado+J%22">Aguado J</searchLink>; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy.; University of Colorado Anschutz Medical Campus, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Contu+L%22">Contu L</searchLink>; Center for Human Technologies, Non-coding RNAs and RNA-based Therapeutics, Istituto Italiano di Tecnologia (IIT), Genova, Italy.<br /><searchLink fieldCode="AU" term="%22di+Lillo+A%22">di Lillo A</searchLink>; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Boggio+S%22">Boggio S</searchLink>; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Tavella+S%22">Tavella S</searchLink>; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy.; Institute of Molecular Genetics (IGM), National Research Institute (CNR), Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Rosso+I%22">Rosso I</searchLink>; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Gustincich+S%22">Gustincich S</searchLink>; Center for Human Technologies, Non-coding RNAs and RNA-based Therapeutics, Istituto Italiano di Tecnologia (IIT), Genova, Italy.<br /><searchLink fieldCode="AU" term="%22Chiti+F%22">Chiti F</searchLink>; Department of Experimental and Clinical Biomedical Sciences, Section of Biochemistry, University of Florence, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22d'Adda+di+Fagagna+F%22">d'Adda di Fagagna F</searchLink>; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy. fabrizio.dadda@igm.cnr.it.; Institute of Molecular Genetics (IGM), National Research Institute (CNR), Pavia, Italy. fabrizio.dadda@igm.cnr.it.
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  Data: <searchLink fieldCode="JN" term="%228208664%22">The EMBO journal</searchLink> [EMBO J] 2025 Nov; Vol. 44 (21), pp. 6078-6111. <i>Date of Electronic Publication: </i>2025 Sep 21.
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