Does lifestyle explain the relationship between socioeconomic position and multimorbidity of cancer and cardiometabolic diseases? A mediation analysis applied to the European Prospective Investigation into Cancer and Nutrition.

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Title: Does lifestyle explain the relationship between socioeconomic position and multimorbidity of cancer and cardiometabolic diseases? A mediation analysis applied to the European Prospective Investigation into Cancer and Nutrition.
Authors: Manfredi L; Centre for Biostatistics, Epidemiology, and Public Health, Department of Clinical and Biological Sciences, University of Turin, Orbassano, Italy luca.manfredi@unito.it., Buscema F; Centre for Biostatistics, Epidemiology, and Public Health, Department of Clinical and Biological Sciences, University of Turin, Orbassano, Italy., Giraudo MT; Centre for Biostatistics, Epidemiology, and Public Health, Department of Clinical and Biological Sciences, University of Turin, Orbassano, Italy., Sodano B; Centre for Biostatistics, Epidemiology, and Public Health, Department of Clinical and Biological Sciences, University of Turin, Orbassano, Italy.; Statistics, Computer Science, Applications, University of Florence, Florence, Italy., Padroni L; Centre for Biostatistics, Epidemiology, and Public Health, Department of Clinical and Biological Sciences, University of Turin, Orbassano, Italy., Destefanis C; Centre for Biostatistics, Epidemiology, and Public Health, Department of Clinical and Biological Sciences, University of Turin, Orbassano, Italy., Freisling H; International Agency for Research on Cancer, Lyon, France., Ferrari P; International Agency for Research on Cancer, Lyon, France., Cesaroni G; Department of Epidemiology, Lazio Region Health Service, Rome, Italy., Uzzau S; Department of Biomedical Sciences, Unit of Microbiology and Virology, University of Sassari, Sassari, Italy., Schulze MB; Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany.; Institute of Nutritional Science, University of Potsdam, Nuthetal, Germany., Saieva C; Clinical Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network, Florence, Italy., Tumino R; Hyblean Association for Epidemiology Research, AIRE - ONLUS, Ragusa, Italy., Weiderpass E; International Agency for Research on Cancer, Lyon, France., Matta K; International Agency for Research on Cancer, Lyon, France., Vaccarella S; International Agency for Research on Cancer, Lyon, France., Guevara M; Instituto de Salud Pública y Laboral de Navarra, Pamplona, Spain.; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública, Madrid, Spain.; Navarra Institute for Health Research, Pamplona, Spain., Halkjær J; Danish Cancer Society Institute of Cancer Biology, Copenhagen, Denmark., Tjønneland A; The Institute of Cancer Epidemiology, Danish Cancer Society Research Center, Unit of Diet, Genes and Environment, Copenhagen, Denmark., Crous-Bou M; Unit of Nutrition and Cancer, Catalan Institute of Oncology Cancer Epidemiology Research Programme, Barcelona, Spain.; Department of Epidemiology, Harvard T H Chan School of Public Health, Boston, Massachusetts, USA., Katzke V; Deutsches Krebsforschungszentrum, Heidelberg, Germany.; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany., Pour T; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany., Panico S; Dipartimento di Medicina Clinica e Chirurgia, Università degli Studi di Napoli Federico II, Napoli, Italy., Pala V; Epidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Tzoulaki I; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Biomedical Research Foundation Academy of Athens, Athens, Greece., Tin Tin S; Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Dahm CC; Department of Public Health, Section for Epidemiology, Aarhus University, Aarhus, UK., Chirlaque M; CIBER Epidemiology and Public Health CIBERESP, Madrid, Spain.; Department of Epidemiology, Regional Health Council, IMIB-Arrixaca, University of Murcia, Murcia, Spain., Sacerdote C; Department of Health Sciences, University of Eastern Piedmont, Novara, Italy., Ricceri F; Centre for Biostatistics, Epidemiology, and Public Health, Department of Clinical and Biological Sciences, University of Turin, Orbassano, Italy.
Source: Journal of epidemiology and community health [J Epidemiol Community Health] 2025 Dec 10; Vol. 80 (1), pp. 3-9. Date of Electronic Publication: 2025 Dec 10.
Publication Type: Journal Article
Journal Info: Publisher: British Medical Assn Country of Publication: England NLM ID: 7909766 Publication Model: Electronic Cited Medium: Internet ISSN: 1470-2738 (Electronic) Linking ISSN: 0143005X NLM ISO Abbreviation: J Epidemiol Community Health Subsets: MEDLINE
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  Data: Does lifestyle explain the relationship between socioeconomic position and multimorbidity of cancer and cardiometabolic diseases? A mediation analysis applied to the European Prospective Investigation into Cancer and Nutrition.
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  Data: <searchLink fieldCode="AU" term="%22Manfredi+L%22">Manfredi L</searchLink>; Centre for Biostatistics, Epidemiology, and Public Health, Department of Clinical and Biological Sciences, University of Turin, Orbassano, Italy luca.manfredi@unito.it.<br /><searchLink fieldCode="AU" term="%22Buscema+F%22">Buscema F</searchLink>; Centre for Biostatistics, Epidemiology, and Public Health, Department of Clinical and Biological Sciences, University of Turin, Orbassano, Italy.<br /><searchLink fieldCode="AU" term="%22Giraudo+MT%22">Giraudo MT</searchLink>; Centre for Biostatistics, Epidemiology, and Public Health, Department of Clinical and Biological Sciences, University of Turin, Orbassano, Italy.<br /><searchLink fieldCode="AU" term="%22Sodano+B%22">Sodano B</searchLink>; Centre for Biostatistics, Epidemiology, and Public Health, Department of Clinical and Biological Sciences, University of Turin, Orbassano, Italy.; Statistics, Computer Science, Applications, University of Florence, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Padroni+L%22">Padroni L</searchLink>; Centre for Biostatistics, Epidemiology, and Public Health, Department of Clinical and Biological Sciences, University of Turin, Orbassano, Italy.<br /><searchLink fieldCode="AU" term="%22Destefanis+C%22">Destefanis C</searchLink>; Centre for Biostatistics, Epidemiology, and Public Health, Department of Clinical and Biological Sciences, University of Turin, Orbassano, Italy.<br /><searchLink fieldCode="AU" term="%22Freisling+H%22">Freisling H</searchLink>; International Agency for Research on Cancer, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Ferrari+P%22">Ferrari P</searchLink>; International Agency for Research on Cancer, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Cesaroni+G%22">Cesaroni G</searchLink>; Department of Epidemiology, Lazio Region Health Service, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Uzzau+S%22">Uzzau S</searchLink>; Department of Biomedical Sciences, Unit of Microbiology and Virology, University of Sassari, Sassari, Italy.<br /><searchLink fieldCode="AU" term="%22Schulze+MB%22">Schulze MB</searchLink>; Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany.; Institute of Nutritional Science, University of Potsdam, Nuthetal, Germany.<br /><searchLink fieldCode="AU" term="%22Saieva+C%22">Saieva C</searchLink>; Clinical Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Tumino+R%22">Tumino R</searchLink>; Hyblean Association for Epidemiology Research, AIRE - ONLUS, Ragusa, Italy.<br /><searchLink fieldCode="AU" term="%22Weiderpass+E%22">Weiderpass E</searchLink>; International Agency for Research on Cancer, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Matta+K%22">Matta K</searchLink>; International Agency for Research on Cancer, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Vaccarella+S%22">Vaccarella S</searchLink>; International Agency for Research on Cancer, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Guevara+M%22">Guevara M</searchLink>; Instituto de Salud Pública y Laboral de Navarra, Pamplona, Spain.; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública, Madrid, Spain.; Navarra Institute for Health Research, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Halkjær+J%22">Halkjær J</searchLink>; Danish Cancer Society Institute of Cancer Biology, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Tjønneland+A%22">Tjønneland A</searchLink>; The Institute of Cancer Epidemiology, Danish Cancer Society Research Center, Unit of Diet, Genes and Environment, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Crous-Bou+M%22">Crous-Bou M</searchLink>; Unit of Nutrition and Cancer, Catalan Institute of Oncology Cancer Epidemiology Research Programme, Barcelona, Spain.; Department of Epidemiology, Harvard T H Chan School of Public Health, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Katzke+V%22">Katzke V</searchLink>; Deutsches Krebsforschungszentrum, Heidelberg, Germany.; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Pour+T%22">Pour T</searchLink>; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Panico+S%22">Panico S</searchLink>; Dipartimento di Medicina Clinica e Chirurgia, Università degli Studi di Napoli Federico II, Napoli, Italy.<br /><searchLink fieldCode="AU" term="%22Pala+V%22">Pala V</searchLink>; Epidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Tzoulaki+I%22">Tzoulaki I</searchLink>; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Biomedical Research Foundation Academy of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Tin+Tin+S%22">Tin Tin S</searchLink>; Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Dahm+CC%22">Dahm CC</searchLink>; Department of Public Health, Section for Epidemiology, Aarhus University, Aarhus, UK.<br /><searchLink fieldCode="AU" term="%22Chirlaque+M%22">Chirlaque M</searchLink>; CIBER Epidemiology and Public Health CIBERESP, Madrid, Spain.; Department of Epidemiology, Regional Health Council, IMIB-Arrixaca, University of Murcia, Murcia, Spain.<br /><searchLink fieldCode="AU" term="%22Sacerdote+C%22">Sacerdote C</searchLink>; Department of Health Sciences, University of Eastern Piedmont, Novara, Italy.<br /><searchLink fieldCode="AU" term="%22Ricceri+F%22">Ricceri F</searchLink>; Centre for Biostatistics, Epidemiology, and Public Health, Department of Clinical and Biological Sciences, University of Turin, Orbassano, Italy.
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