A Bioinspired Lipopeptide Surmounts Therapeutic Dilemmas of Gram-Positive and Gram-Negative Polymicrobial Infection.

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Title: A Bioinspired Lipopeptide Surmounts Therapeutic Dilemmas of Gram-Positive and Gram-Negative Polymicrobial Infection.
Authors: Zou D; Department of Pharmacy, College of Biology, Hunan University, Changsha, Hunan 410082, China.; State Key Laboratory of Chemo and Biosensing, Hunan Research Center of the Basic Discipline for Cell Signaling, Hunan Provincial Key Laboratory of Medical Virology, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Hunan Engineering Research Center for Anticancer Targeted Protein Pharmaceuticals, Hunan University, Changsha, Hunan 410082, China., Deng K; Department of Pharmacy, College of Biology, Hunan University, Changsha, Hunan 410082, China., Zeng Z; Department of Pharmacy, College of Biology, Hunan University, Changsha, Hunan 410082, China., Gong W; Department of Pharmacy, College of Biology, Hunan University, Changsha, Hunan 410082, China., Guo B; Department of Pharmacy, College of Biology, Hunan University, Changsha, Hunan 410082, China., Liu Y; Department of Pharmacy, College of Biology, Hunan University, Changsha, Hunan 410082, China., Xie Y; Department of Pharmacy, College of Biology, Hunan University, Changsha, Hunan 410082, China., Li Y; Department of Pharmacy, College of Biology, Hunan University, Changsha, Hunan 410082, China.; State Key Laboratory of Chemo and Biosensing, Hunan Research Center of the Basic Discipline for Cell Signaling, Hunan Provincial Key Laboratory of Medical Virology, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Hunan Engineering Research Center for Anticancer Targeted Protein Pharmaceuticals, Hunan University, Changsha, Hunan 410082, China., Xu X; Department of Pharmacy, College of Biology, Hunan University, Changsha, Hunan 410082, China.; State Key Laboratory of Chemo and Biosensing, Hunan Research Center of the Basic Discipline for Cell Signaling, Hunan Provincial Key Laboratory of Medical Virology, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Hunan Engineering Research Center for Anticancer Targeted Protein Pharmaceuticals, Hunan University, Changsha, Hunan 410082, China.
Source: Journal of the American Chemical Society [J Am Chem Soc] 2025 Oct 08; Vol. 147 (40), pp. 36339-36351. Date of Electronic Publication: 2025 Sep 23.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1520-5126
DOI:10.1021/jacs.5c10219