Anti-inflammatory and anti-nociceptive effects of individualized blood pressure strategy based on low-dose noradrenaline infusion in elderly patients following major surgery: A randomized, controlled study.

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Title: Anti-inflammatory and anti-nociceptive effects of individualized blood pressure strategy based on low-dose noradrenaline infusion in elderly patients following major surgery: A randomized, controlled study.
Authors: Fang Z; Department of Anesthesiology, First Affiliated Hospital of Anhui Medical University and Key Laboratory of Anesthesiology and Perioperative Medicine of Anhui Higher Education Institutes, Anhui Medical University, Hefei, China., Wang YJ; Department of Anesthesiology, First Affiliated Hospital of Anhui Medical University and Key Laboratory of Anesthesiology and Perioperative Medicine of Anhui Higher Education Institutes, Anhui Medical University, Hefei, China., Zhu XH; Department of Anesthesiology, First Affiliated Hospital of Anhui Medical University and Key Laboratory of Anesthesiology and Perioperative Medicine of Anhui Higher Education Institutes, Anhui Medical University, Hefei, China., Zheng JH; Department of Anesthesiology, First Affiliated Hospital of Anhui Medical University and Key Laboratory of Anesthesiology and Perioperative Medicine of Anhui Higher Education Institutes, Anhui Medical University, Hefei, China., Liu W; Department of Anesthesiology, Taihe Traditional Chinese Medicine Hospital, Fuyan, China., Gu E; Department of Anesthesiology, First Affiliated Hospital of Anhui Medical University and Key Laboratory of Anesthesiology and Perioperative Medicine of Anhui Higher Education Institutes, Anhui Medical University, Hefei, China. Electronic address: ay_guew_mz@163.com., Cheng XQ; Department of Anesthesiology, First Affiliated Hospital of Anhui Medical University and Key Laboratory of Anesthesiology and Perioperative Medicine of Anhui Higher Education Institutes, Anhui Medical University, Hefei, China. Electronic address: ay_mz_cheng@126.com.
Source: Journal of clinical anesthesia [J Clin Anesth] 2025 Nov; Vol. 107, pp. 111978. Date of Electronic Publication: 2025 Sep 23.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 8812166 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4529 (Electronic) Linking ISSN: 09528180 NLM ISO Abbreviation: J Clin Anesth Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-4529
DOI:10.1016/j.jclinane.2025.111978