MYC-driven gliosis impairs neuron-glia communication in amyotrophic lateral sclerosis.

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Bibliographic Details
Title: MYC-driven gliosis impairs neuron-glia communication in amyotrophic lateral sclerosis.
Authors: Fioretti PV; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento 38123, Italy., Barbieri A; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento 38123, Italy., Migazzi A; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento 38123, Italy., Bressan D; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento 38123, Italy., Grassano M; 'Rita Levi Montalcini' Department of Neuroscience, ALS Centre, University of Turin, Turin 10126, Italy.; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA., Donini L; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento 38123, Italy., Roccuzzo M; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento 38123, Italy.; Department CIBIO, Advanced Imaging Core Facility (AICF), University of Trento, Trento 38123, Italy., Torrieri MC; 'Rita Levi Montalcini' Department of Neuroscience, ALS Centre, University of Turin, Turin 10126, Italy., Conci F; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento 38123, Italy., Ferracci E; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento 38123, Italy., Invernizzi S; Department Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, Milan 20122, Italy., Bowden KM; Sheffield Institute for Translational Neuroscience, School of Medicine and Population Health, University of Sheffield, Sheffield S10 2HQ, UK., Bacchetti F; Department of Pharmacy, Pharmacology and Toxicology Unit, University of Genoa, Genoa 16132, Italy., Cappelli S; International Centre for Genetic Engineering and Biotechnology, Trieste 34149, Italy., Peroni D; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento 38123, Italy.; Department CIBIO, Proteomics and Mass Spectrometry Core Facility (MS), University of Trento, Trento 38123, Italy., Belli R; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento 38123, Italy.; Department CIBIO, Proteomics and Mass Spectrometry Core Facility (MS), University of Trento, Trento 38123, Italy., Pancher M; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento 38123, Italy.; Department CIBIO, High Throughput Screening and Validation Core Facility (HTS), University of Trento, Trento 38123, Italy., Mugoni V; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento 38123, Italy., Scarduelli G; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento 38123, Italy.; Department CIBIO, Advanced Imaging Core Facility (AICF), University of Trento, Trento 38123, Italy., Gianesello M; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento 38123, Italy., Pasetto L; Research Center for ALS, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan 20156, Italy., Canarutto G; International Centre for Genetic Engineering and Biotechnology, Trieste 34149, Italy.; Department of Life Sciences, University of Trieste, Trieste 34127, Italy., Carra S; Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena 41125, Italy., Soldano A; Department of Neuroscience, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Trieste 34136, Italy., Bisio A; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento 38123, Italy., Robbiati S; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento 38123, Italy.; Department CIBIO, Model Organism Core Facility (MOF), University of Trento, Trento 38123, Italy., Valentini C; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento 38123, Italy.; Department CIBIO, Next Generation Sequencing Core Facility (NGS), University of Trento, Trento 38123, Italy., Nardella C; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento 38123, Italy., Piazza S; International Centre for Genetic Engineering and Biotechnology, Trieste 34149, Italy.; Department of Life Sciences, University of Trieste, Trieste 34127, Italy., D'Agostino VG; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento 38123, Italy., Quattrone A; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento 38123, Italy., Sleiman S; Department of Biological Sciences, Lebanese American University, PO Box 36, Byblos, Lebanon., Whitfield JR; Vall d'Hebron Institute of Oncology, Cellex Centre, Hospital University Vall d'Hebron Campus, Barcelona 08035, Spain., Soucek L; Vall d'Hebron Institute of Oncology, Cellex Centre, Hospital University Vall d'Hebron Campus, Barcelona 08035, Spain.; Institució Catalana de Recerca i Estudis Avançats, Barcelona 08010, Spain.; Department of Biochemistry and Molecular Biology, Universitat Autonoma de Barcelona, Bellaterra 08193, Spain.; Peptomyc S.L., Barcelona 08035, Spain., Vignoli B; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento 38123, Italy., Viero G; CNR Unit Trento, Institute of Biophysics, Trento 38123, Italy., Tiberi L; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento 38123, Italy., Zippo A; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento 38123, Italy., Demichelis F; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento 38123, Italy., Bonetto V; Research Center for ALS, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan 20156, Italy., Milanese M; Department of Pharmacy, Pharmacology and Toxicology Unit, University of Genoa, Genoa 16132, Italy.; IRCCS Ospedale Policlinico San Martino, Genoa 16132, Italy., Buratti E; International Centre for Genetic Engineering and Biotechnology, Trieste 34149, Italy., Verde F; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan 20145, Italy.; Department of Pathophysiology and Transplantation (DEPT), Dino Ferrari Center, Università degli Studi di Milano, Milan 20122, Italy., Ticozzi N; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan 20145, Italy.; Department of Pathophysiology and Transplantation (DEPT), Dino Ferrari Center, Università degli Studi di Milano, Milan 20122, Italy., Calvo A; 'Rita Levi Montalcini' Department of Neuroscience, ALS Centre, University of Turin, Turin 10126, Italy.; Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino, SC Neurologia 1U, Turin 10126, Italy., Ratti A; Department Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, Milan 20122, Italy.; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan 20145, Italy., Shaw PJ; Sheffield Institute for Translational Neuroscience, School of Medicine and Population Health, University of Sheffield, Sheffield S10 2HQ, UK.; The NIHR Sheffield Biomedical Research Centre, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield S10 2JF, UK., Terenzio M; Molecular Neuroscience Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa 904-0495, Japan., Chiacchiera F; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento 38123, Italy., Pennuto M; Department of Biomedical Sciences (DBS), University of Padova, Padova 35131, Italy.; Veneto Institute of Molecular Medicine (VIMM), Padova 35129, Italy., Basso M; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento 38123, Italy.
Source: Brain : a journal of neurology [Brain] 2026 May 05; Vol. 149 (5), pp. 1604-1622.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print Cited Medium: Internet ISSN: 1460-2156 (Electronic) Linking ISSN: 00068950 NLM ISO Abbreviation: Brain Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1460-2156
DOI:10.1093/brain/awaf360