Spatially-restricted inflammation-induced senescent-like glia in multiple sclerosis and patient-derived organoids.
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| Title: | Spatially-restricted inflammation-induced senescent-like glia in multiple sclerosis and patient-derived organoids. |
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| Authors: | Fagiani F; Translational Neuropathology Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy., Pedrini E; Translational Neuropathology Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy., Martire MS; Translational Neuropathology Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Neurology Unit, IRCCS San Raffaele Hospital, Milan, Italy., Gastoldi G; Translational Neuropathology Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy., Vanden Bulcke C; Louvain Neuroinflammation Imaging Lab, Institute of NeuroScience, Université Catholique de Louvain, Brussels, Belgium., Lin JP; Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA., Maric D; Flow and Imaging Cytometry Core Facility, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA., Brambilla E; Neuroimmunology Unit, Division of Neuroscience, IRCCS San Raffaele Hospital, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Ruffini F; Neuroimmunology Unit, Division of Neuroscience, IRCCS San Raffaele Hospital, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Peri C; Neuroimmunology Unit, Division of Neuroscience, IRCCS San Raffaele Hospital, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Calabresi PA; Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD, USA., Maggi P; Louvain Neuroinflammation Imaging Lab, Institute of NeuroScience, Université Catholique de Louvain, Brussels, Belgium., Panina-Bordignon P; Neuroimmunology Unit, Division of Neuroscience, IRCCS San Raffaele Hospital, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Martino G; Neuroimmunology Unit, Division of Neuroscience, IRCCS San Raffaele Hospital, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Reich DS; Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA., Absinta M; Department of Biomedical Sciences, Humanitas University, Milan, Italy. martina.absinta@hunimed.eu.; Experimental Neuropathology Lab, IRCCS Humanitas Research Hospital, Milan, Italy. martina.absinta@hunimed.eu. |
| Source: | Nature communications [Nat Commun] 2025 Sep 26; Vol. 16 (1), pp. 8477. Date of Electronic Publication: 2025 Sep 26. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-63371-9 |
