Intramuscular enteric glia persist in Hirschsprung disease and undergo neurogenesis in response to GDNF-NCAM1 signaling.
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| Title: | Intramuscular enteric glia persist in Hirschsprung disease and undergo neurogenesis in response to GDNF-NCAM1 signaling. |
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| Authors: | Mueller JL; Department of Pediatric Surgery, Harvard Medical School, Massachusetts General Hospital, 55 Fruit St, Warren 1151, Boston, MA, 02114, USA., Han C; Department of Pediatric Surgery, Harvard Medical School, Massachusetts General Hospital, 55 Fruit St, Warren 1151, Boston, MA, 02114, USA., Leavitt A; Department of Pediatric Surgery, Harvard Medical School, Massachusetts General Hospital, 55 Fruit St, Warren 1151, Boston, MA, 02114, USA., Chauhan V; Department of Pediatric Surgery, Harvard Medical School, Massachusetts General Hospital, 55 Fruit St, Warren 1151, Boston, MA, 02114, USA., Ott L; Department of Pediatric Surgery, Harvard Medical School, Massachusetts General Hospital, 55 Fruit St, Warren 1151, Boston, MA, 02114, USA., Guyer RA; Department of Pediatric Surgery, Harvard Medical School, Massachusetts General Hospital, 55 Fruit St, Warren 1151, Boston, MA, 02114, USA., Uesaka T; Department of Physiology and Cell Biology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan., Enomoto H; Department of Physiology and Cell Biology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan., Cheng L; Department of Pediatric Surgery, University of Virginia, Charlottesville, VA, 22908, USA., Hotta R; Department of Pediatric Surgery, Harvard Medical School, Massachusetts General Hospital, 55 Fruit St, Warren 1151, Boston, MA, 02114, USA., Burns AJ; Department of Pediatric Surgery, Harvard Medical School, Massachusetts General Hospital, 55 Fruit St, Warren 1151, Boston, MA, 02114, USA., Stavely R; Department of Pediatric Surgery, Harvard Medical School, Massachusetts General Hospital, 55 Fruit St, Warren 1151, Boston, MA, 02114, USA., Goldstein AM; Department of Pediatric Surgery, Harvard Medical School, Massachusetts General Hospital, 55 Fruit St, Warren 1151, Boston, MA, 02114, USA. amgoldstein@mgb.org. |
| Source: | Scientific reports [Sci Rep] 2025 Sep 26; Vol. 15 (1), pp. 33200. Date of Electronic Publication: 2025 Sep 26. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2045-2322 |
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| DOI: | 10.1038/s41598-025-17734-3 |
