Intramuscular enteric glia persist in Hirschsprung disease and undergo neurogenesis in response to GDNF-NCAM1 signaling.

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Title: Intramuscular enteric glia persist in Hirschsprung disease and undergo neurogenesis in response to GDNF-NCAM1 signaling.
Authors: Mueller JL; Department of Pediatric Surgery, Harvard Medical School, Massachusetts General Hospital, 55 Fruit St, Warren 1151, Boston, MA, 02114, USA., Han C; Department of Pediatric Surgery, Harvard Medical School, Massachusetts General Hospital, 55 Fruit St, Warren 1151, Boston, MA, 02114, USA., Leavitt A; Department of Pediatric Surgery, Harvard Medical School, Massachusetts General Hospital, 55 Fruit St, Warren 1151, Boston, MA, 02114, USA., Chauhan V; Department of Pediatric Surgery, Harvard Medical School, Massachusetts General Hospital, 55 Fruit St, Warren 1151, Boston, MA, 02114, USA., Ott L; Department of Pediatric Surgery, Harvard Medical School, Massachusetts General Hospital, 55 Fruit St, Warren 1151, Boston, MA, 02114, USA., Guyer RA; Department of Pediatric Surgery, Harvard Medical School, Massachusetts General Hospital, 55 Fruit St, Warren 1151, Boston, MA, 02114, USA., Uesaka T; Department of Physiology and Cell Biology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan., Enomoto H; Department of Physiology and Cell Biology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan., Cheng L; Department of Pediatric Surgery, University of Virginia, Charlottesville, VA, 22908, USA., Hotta R; Department of Pediatric Surgery, Harvard Medical School, Massachusetts General Hospital, 55 Fruit St, Warren 1151, Boston, MA, 02114, USA., Burns AJ; Department of Pediatric Surgery, Harvard Medical School, Massachusetts General Hospital, 55 Fruit St, Warren 1151, Boston, MA, 02114, USA., Stavely R; Department of Pediatric Surgery, Harvard Medical School, Massachusetts General Hospital, 55 Fruit St, Warren 1151, Boston, MA, 02114, USA., Goldstein AM; Department of Pediatric Surgery, Harvard Medical School, Massachusetts General Hospital, 55 Fruit St, Warren 1151, Boston, MA, 02114, USA. amgoldstein@mgb.org.
Source: Scientific reports [Sci Rep] 2025 Sep 26; Vol. 15 (1), pp. 33200. Date of Electronic Publication: 2025 Sep 26.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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