Alzheimer's disease diagnostic progression is associated with cerebrovascular disease and neuroinflammation in adults with Down syndrome.
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| Title: | Alzheimer's disease diagnostic progression is associated with cerebrovascular disease and neuroinflammation in adults with Down syndrome. |
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| Authors: | Edwards NC; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York City, New York, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, New York, USA.; Department of Neuroscience, Columbia University, New York City, New York, USA., Lao PJ; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York City, New York, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, New York, USA., Alshikho MJ; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York City, New York, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, New York, USA., Ericsson OM; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York City, New York, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, New York, USA., Rizvi B; Department of Neurobiology & Behavior, University of California, Irvine, California, USA., Petersen ME; University of North Texas Health Science Center, Fort Worth, Texas, USA., O'Bryant S; University of North Texas Health Science Center, Fort Worth, Texas, USA., Flores-Aguilar L; Department of Pathology and Laboratory Medicine, University of California Irvine School of Medicine, University of California, Irvine, California, USA., Simoes S; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York City, New York, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, New York, USA., Mapstone M; Department of Neurology, University of California, Irvine, California, USA., Tudorascu DL; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Janelidze S; Department of Clinical Sciences Malmö, Clinical Memory Research Unit, Lund University, Lund, Sweden., Hansson O; Department of Clinical Sciences Malmö, Clinical Memory Research Unit, Lund University, Lund, Sweden.; Memory Clinic, Skåne University Hospital, Malmö, Sweden., Handen BL; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Christian BT; Waisman Center, University of Wisconsin-Madison, Madison, Wisconsin, USA., Lee JH; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York City, New York, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, New York, USA., Lai F; Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA., Rosas HD; Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA.; Department of Radiology, Center for Neuroimaging of Aging and Neurodegenerative Diseases, Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, Massachusetts, USA., Zaman S; Department of Psychiatry, University of Cambridge, Cambridge, UK., Lott IT; Department of Pediatrics and Neurology, School of Medicine, University of California, Irvine, California, USA., Yassa MA; Department of Neurobiology & Behavior, University of California, Irvine, California, USA.; Center for the Neurobiology of Learning and Memory, University of California, Irvine, California, USA., Gutierrez J; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, New York, USA., Wilcock DM; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Department of Neurology, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Department of Anatomy, Cell Biology and Physiology, Indiana University School of Medicine, Indianapolis, Indiana, USA., Head E; Department of Pathology and Laboratory Medicine, University of California Irvine School of Medicine, University of California, Irvine, California, USA., Brickman AM; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York City, New York, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, New York, USA. |
| Corporate Authors: | Alzheimer's Biomarkers Consortium–Down Syndrome (ABC‐DS) Investigators |
| Source: | Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2025 Oct; Vol. 21 (10), pp. e70726. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1552-5279 |
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| DOI: | 10.1002/alz.70726 |
