Polygenic risk score for breast cancer risk prediction in Asian BRCA1 and BRCA2 pathogenic variants carriers.
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| Title: | Polygenic risk score for breast cancer risk prediction in Asian BRCA1 and BRCA2 pathogenic variants carriers. |
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| Authors: | Tai MC; Cancer Research Malaysia, Subang Jaya, Selangor, Malaysia., Dennis J; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Park SK; Department of Preventive Medicine, Seoul National University College of Medicine, Jongno-gu, Seoul, Korea.; Cancer Research Institute, Seoul National University, Jongno-gu, Seoul, Korea.; Integrated Major in Innovative Medical Science, Seoul National University College of Medicine, Jongno-gu, Seoul, Korea., Kim SW; Department of Surgery, Daerim St. Mary's Hospital, Yeongdeungpo-gu, Seoul, Korea., Lee JW; Department of Surgery, Ulsan College of Medicine and Asan Medical Center, Songpa-Gu, Seoul, Korea., Hassan NT; Cancer Research Malaysia, Subang Jaya, Selangor, Malaysia., Kwong A; Cancer Genetics Centre and Breast Surgery Centre, Hong Kong Sanatorium and Hospital, Hong Kong, Hong Kong.; Hong Kong Hereditary Breast Cancer Family Registry, Hong Kong, Hong Kong.; Division of Breast Surgery, Department of Surgery, The University of Hong Kong, Hong Kong, Hong Kong., Hartman M; Department of Surgery, National University Hospital and National University Health System, Singapore, Singapore.; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore., Yoon SY; Cancer Research Malaysia, Subang Jaya, Selangor, Malaysia., Ngeow J; Cancer Genetics Service, National Cancer Centre Singapore, Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Woo YL; Department of Obstetrics and Gynaecology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Park B; Department of Preventive Medicine, Hanyang University College of Medicine, Seoul, South Korea., Wong ZL; Cancer Research Malaysia, Subang Jaya, Selangor, Malaysia., Leslie G; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Bolla MK; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Barnes DR; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Parsons MT; Public Health Division, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Soucy P; Genomics Center, CHU de Québec-Université Laval Research Center, Québec, Canada., Simard J; Genomics Center, CHU de Québec-Université Laval Research Center, Québec, Canada., Mohd Taib NA; Department of Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.; University Malaya Cancer Research Institute (UMCRI), University of Malaya, Kuala Lumpur, Kuala Lumpur, Malaysia., Yip CH; Sime Darby Medical Centre, Subang Jaya, Selangor, Malaysia.; Picaso Hospital, Petaling Jaya, Malaysia., Easton DF; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Chenevix-Trench G; Department of Haematology-Oncology, University of Adelaide, The Queen Elizabeth Hospital, Woodville, SA, Australia., Antoniou AC; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Teo SH; Cancer Research Malaysia, Subang Jaya, Selangor, Malaysia.; Department of Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Ho WK; Cancer Research Malaysia, Subang Jaya, Selangor, Malaysia. WeangKee.Ho@nottingham.edu.my.; School of Mathematical Sciences, Faculty of Science and Engineering, University of Nottingham Malaysia, Semenyih, Selangor, Malaysia. WeangKee.Ho@nottingham.edu.my. |
| Source: | NPJ breast cancer [NPJ Breast Cancer] 2025 Sep 30; Vol. 11 (1), pp. 105. Date of Electronic Publication: 2025 Sep 30. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Breast Cancer Research Foundation Country of Publication: United States NLM ID: 101674891 Publication Model: Electronic Cited Medium: Print ISSN: 2374-4677 (Print) Linking ISSN: 23744677 NLM ISO Abbreviation: NPJ Breast Cancer Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2374-4677 |
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| DOI: | 10.1038/s41523-025-00820-0 |
