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BiTE-secreting T cells rationally combine with PD-1 blockade and vaccine boosting to reshape antitumor immunity in ovarian cancer.

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Bibliographic Details
Title: BiTE-secreting T cells rationally combine with PD-1 blockade and vaccine boosting to reshape antitumor immunity in ovarian cancer.
Authors: Chiello JL; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Shaikh N; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Jacobi J; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Gaulin N; Department of Gynecologic Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Santos G; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Keck C; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Hess SM; Department of Gynecologic Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Lichty B; McMaster Immunology Research Centre, McMaster University, Hamilton, ON L8R2K3, Canada., Singh PK; Department of Cancer Genetics and Genomics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Rosario SR; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Abrams SI; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Zsiros E; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA; Department of Gynecologic Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Long MD; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA. Electronic address: mark.long@roswellpark.org., McGray AJR; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA; Department of Gynecologic Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA. Electronic address: ajrobert.mcgray@roswellpark.org.
Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2026 Jan 07; Vol. 34 (1), pp. 455-478. Date of Electronic Publication: 2025 Sep 30.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1525-0024
DOI:10.1016/j.ymthe.2025.09.047