BiTE-secreting T cells rationally combine with PD-1 blockade and vaccine boosting to reshape antitumor immunity in ovarian cancer.

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Title: BiTE-secreting T cells rationally combine with PD-1 blockade and vaccine boosting to reshape antitumor immunity in ovarian cancer.
Authors: Chiello JL; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Shaikh N; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Jacobi J; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Gaulin N; Department of Gynecologic Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Santos G; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Keck C; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Hess SM; Department of Gynecologic Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Lichty B; McMaster Immunology Research Centre, McMaster University, Hamilton, ON L8R2K3, Canada., Singh PK; Department of Cancer Genetics and Genomics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Rosario SR; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Abrams SI; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Zsiros E; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA; Department of Gynecologic Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA., Long MD; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA. Electronic address: mark.long@roswellpark.org., McGray AJR; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA; Department of Gynecologic Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA. Electronic address: ajrobert.mcgray@roswellpark.org.
Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2026 Jan 07; Vol. 34 (1), pp. 455-478. Date of Electronic Publication: 2025 Sep 30.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: BiTE-secreting T cells rationally combine with PD-1 blockade and vaccine boosting to reshape antitumor immunity in ovarian cancer.
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  Data: <searchLink fieldCode="AU" term="%22Chiello+JL%22">Chiello JL</searchLink>; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.<br /><searchLink fieldCode="AU" term="%22Shaikh+N%22">Shaikh N</searchLink>; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.<br /><searchLink fieldCode="AU" term="%22Jacobi+J%22">Jacobi J</searchLink>; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.<br /><searchLink fieldCode="AU" term="%22Gaulin+N%22">Gaulin N</searchLink>; Department of Gynecologic Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.<br /><searchLink fieldCode="AU" term="%22Santos+G%22">Santos G</searchLink>; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.<br /><searchLink fieldCode="AU" term="%22Keck+C%22">Keck C</searchLink>; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.<br /><searchLink fieldCode="AU" term="%22Hess+SM%22">Hess SM</searchLink>; Department of Gynecologic Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.<br /><searchLink fieldCode="AU" term="%22Lichty+B%22">Lichty B</searchLink>; McMaster Immunology Research Centre, McMaster University, Hamilton, ON L8R2K3, Canada.<br /><searchLink fieldCode="AU" term="%22Singh+PK%22">Singh PK</searchLink>; Department of Cancer Genetics and Genomics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.<br /><searchLink fieldCode="AU" term="%22Rosario+SR%22">Rosario SR</searchLink>; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.<br /><searchLink fieldCode="AU" term="%22Abrams+SI%22">Abrams SI</searchLink>; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.<br /><searchLink fieldCode="AU" term="%22Zsiros+E%22">Zsiros E</searchLink>; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA; Department of Gynecologic Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.<br /><searchLink fieldCode="AU" term="%22Long+MD%22">Long MD</searchLink>; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA. Electronic address: mark.long@roswellpark.org.<br /><searchLink fieldCode="AU" term="%22McGray+AJR%22">McGray AJR</searchLink>; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA; Department of Gynecologic Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA. Electronic address: ajrobert.mcgray@roswellpark.org.
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  Data: <searchLink fieldCode="JN" term="%22100890581%22">Molecular therapy : the journal of the American Society of Gene Therapy</searchLink> [Mol Ther] 2026 Jan 07; Vol. 34 (1), pp. 455-478. <i>Date of Electronic Publication: </i>2025 Sep 30.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>100890581 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1525-0024 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215250016%22">15250016 </searchLink><i>NLM ISO Abbreviation: </i>Mol Ther <i>Subsets: </i>MEDLINE
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