S-nitrosoglutathione reductase as a therapeutic target for diabetic vascular complications in rodent models.
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| Title: | S-nitrosoglutathione reductase as a therapeutic target for diabetic vascular complications in rodent models. |
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| Authors: | Zhao S; Key Laboratory of Drug Targets and Translational Medicine for Cardio-cerebrovascular Diseases; Medical Basic Research Innovation Center for Cardiovascular and Cerebrovascular Diseases, Ministry of Education; Key Laboratory of Targeted Intervention of Cardiovascular Disease; Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University, Nanjing 211166, China., Song T; Key Laboratory of Drug Targets and Translational Medicine for Cardio-cerebrovascular Diseases; Medical Basic Research Innovation Center for Cardiovascular and Cerebrovascular Diseases, Ministry of Education; Key Laboratory of Targeted Intervention of Cardiovascular Disease; Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University, Nanjing 211166, China., Tang X; Key Laboratory of Drug Targets and Translational Medicine for Cardio-cerebrovascular Diseases; Medical Basic Research Innovation Center for Cardiovascular and Cerebrovascular Diseases, Ministry of Education; Key Laboratory of Targeted Intervention of Cardiovascular Disease; Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University, Nanjing 211166, China., Fan C; Key Laboratory of Drug Targets and Translational Medicine for Cardio-cerebrovascular Diseases; Medical Basic Research Innovation Center for Cardiovascular and Cerebrovascular Diseases, Ministry of Education; Key Laboratory of Targeted Intervention of Cardiovascular Disease; Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University, Nanjing 211166, China., Yang Y; Key Laboratory of Drug Targets and Translational Medicine for Cardio-cerebrovascular Diseases; Medical Basic Research Innovation Center for Cardiovascular and Cerebrovascular Diseases, Ministry of Education; Key Laboratory of Targeted Intervention of Cardiovascular Disease; Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University, Nanjing 211166, China., Zhang Z; State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Harbin Medical University, Harbin 150081, China., Xia Y; Institute of Precision Medicine, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China.; Department of Orthopaedics, Shanghai Key Laboratory of Orthopaedic Implant, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China., Zhang Y; Key Laboratory of Drug Targets and Translational Medicine for Cardio-cerebrovascular Diseases; Medical Basic Research Innovation Center for Cardiovascular and Cerebrovascular Diseases, Ministry of Education; Key Laboratory of Targeted Intervention of Cardiovascular Disease; Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University, Nanjing 211166, China., Cao J; Key Laboratory of Drug Targets and Translational Medicine for Cardio-cerebrovascular Diseases; Medical Basic Research Innovation Center for Cardiovascular and Cerebrovascular Diseases, Ministry of Education; Key Laboratory of Targeted Intervention of Cardiovascular Disease; Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University, Nanjing 211166, China., Wang Z; Key Laboratory of Drug Targets and Translational Medicine for Cardio-cerebrovascular Diseases; Medical Basic Research Innovation Center for Cardiovascular and Cerebrovascular Diseases, Ministry of Education; Key Laboratory of Targeted Intervention of Cardiovascular Disease; Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University, Nanjing 211166, China., Shi Z; Key Laboratory of Drug Targets and Translational Medicine for Cardio-cerebrovascular Diseases; Medical Basic Research Innovation Center for Cardiovascular and Cerebrovascular Diseases, Ministry of Education; Key Laboratory of Targeted Intervention of Cardiovascular Disease; Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University, Nanjing 211166, China., Tang X; Department of Thoracic and Cardiovascular Surgery, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008, China.; Nanjing Medical University Drum Tower Clinical Medical College, Nanjing 210008, China., Wang D; Department of Thoracic and Cardiovascular Surgery, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008, China.; Nanjing Medical University Drum Tower Clinical Medical College, Nanjing 210008, China., Yin G; Department of Orthopaedics, First Affiliated Hospital of Nanjing Medical University, Nanjing Medical University, Nanjing 210029, China., Zhang S; Department of Orthopaedics, First Affiliated Hospital of Nanjing Medical University, Nanjing Medical University, Nanjing 210029, China., Gao Y; Key Laboratory of Drug Targets and Translational Medicine for Cardio-cerebrovascular Diseases; Medical Basic Research Innovation Center for Cardiovascular and Cerebrovascular Diseases, Ministry of Education; Key Laboratory of Targeted Intervention of Cardiovascular Disease; Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University, Nanjing 211166, China., Chen H; Key Laboratory of Drug Targets and Translational Medicine for Cardio-cerebrovascular Diseases; Medical Basic Research Innovation Center for Cardiovascular and Cerebrovascular Diseases, Ministry of Education; Key Laboratory of Targeted Intervention of Cardiovascular Disease; Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University, Nanjing 211166, China., Wang L; Department of Cardiology, First Affiliated Hospital of Nanjing Medical University, Nanjing Medical University, Nanjing 210029, China., Chen F; Key Laboratory of Drug Targets and Translational Medicine for Cardio-cerebrovascular Diseases; Medical Basic Research Innovation Center for Cardiovascular and Cerebrovascular Diseases, Ministry of Education; Key Laboratory of Targeted Intervention of Cardiovascular Disease; Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University, Nanjing 211166, China.; Department of Forensic Medicine, Nanjing Medical University, Nanjing 211166, China., Wang H; Center for Metabolic Disease Research, Temple University School of Medicine, Philadelphia, PA 19140, USA., Yu B; State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Harbin Medical University, Harbin 150081, China., Cao Y; Institute of Precision Medicine, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China.; Department of Orthopaedics, Shanghai Key Laboratory of Orthopaedic Implant, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China., Sun K; Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Suzhou 215002, China., Liu X; Center for Zero-to-One Innovation, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100190, China., Wang X; Center for Zero-to-One Innovation, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100190, China., Yan C; State Key Laboratory of Frigid Zone Cardiovascular Diseases, Cardiovascular Research Institute and Department of Cardiology, General Hospital of Northern Theater Command, Shenyang 110003, China., Han Y; State Key Laboratory of Frigid Zone Cardiovascular Diseases, Cardiovascular Research Institute and Department of Cardiology, General Hospital of Northern Theater Command, Shenyang 110003, China., Han Y; Critical Care Department, Second Affiliated Hospital of Harbin Medical University, Harbin 150001, PR China., Xie L; Key Laboratory of Drug Targets and Translational Medicine for Cardio-cerebrovascular Diseases; Medical Basic Research Innovation Center for Cardiovascular and Cerebrovascular Diseases, Ministry of Education; Key Laboratory of Targeted Intervention of Cardiovascular Disease; Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University, Nanjing 211166, China., Ji Y; Key Laboratory of Drug Targets and Translational Medicine for Cardio-cerebrovascular Diseases; Medical Basic Research Innovation Center for Cardiovascular and Cerebrovascular Diseases, Ministry of Education; Key Laboratory of Targeted Intervention of Cardiovascular Disease; Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University, Nanjing 211166, China.; State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Harbin Medical University, Harbin 150081, China. |
| Source: | Science translational medicine [Sci Transl Med] 2025 Oct; Vol. 17 (818), pp. eadn9216. Date of Electronic Publication: 2025 Oct 01. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1946-6242 |
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| DOI: | 10.1126/scitranslmed.adn9216 |
