SFPQ-TFE3 reciprocally regulates mTORC1 and induces lineage plasticity in a mouse model of renal tumorigenesis.
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| Title: | SFPQ-TFE3 reciprocally regulates mTORC1 and induces lineage plasticity in a mouse model of renal tumorigenesis. |
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| Authors: | Asrani K; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. kasrani1@jhmi.edu.; Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. kasrani1@jhmi.edu., Amaral A; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Woo J; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Abadchi SN; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Vidotto T; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Imada E; Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Skaist A; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Feng K; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Liu HB; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Kasbe M; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Satou Y; Division of Genomics and Transcriptomics, Kumamoto University, Kumamoto, Japan., Baba M; Department of Urology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan., Oike Y; Department of Molecular Genetics, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan., Outeda P; University of Maryland, School of Medicine, Baltimore, MD, USA., Watnick T; University of Maryland, School of Medicine, Baltimore, MD, USA., Rosenberg AZ; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Schmidt LS; Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.; Basic Science Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Linehan WM; Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Argani P; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Lotan TL; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. tlotan1@jhmi.edu.; Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. tlotan1@jhmi.edu.; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. tlotan1@jhmi.edu. |
| Source: | Nature communications [Nat Commun] 2025 Oct 03; Vol. 16 (1), pp. 8822. Date of Electronic Publication: 2025 Oct 03. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-63885-2 |
