Adolescent methamphetamine exposure drives neuroinflammation and aberrant neurogenesis linked to anxiety and cognitive impairments in adult mice.

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Title: Adolescent methamphetamine exposure drives neuroinflammation and aberrant neurogenesis linked to anxiety and cognitive impairments in adult mice.
Authors: Ito A; Department of Neuroscience and Cell Biology, Graduate School of Medicine, The University of Osaka, Suita, Japan., Usui N; Department of Neuroscience and Cell Biology, Graduate School of Medicine, The University of Osaka, Suita, Japan. usui@anat1.med.osaka-u.ac.jp.; Omics Center, Center of Medical Innovation and Translational Research, Graduate School of Medicine, The University of Osaka, Suita, Japan. usui@anat1.med.osaka-u.ac.jp.; United Graduate School of Child Development, The University of Osaka, Suita, Japan. usui@anat1.med.osaka-u.ac.jp.; Global Center for Medical Engineering and Informatics, The University of Osaka, Suita, Japan. usui@anat1.med.osaka-u.ac.jp.; Addiction Research Unit, Osaka Psychiatric Research Center, Osaka Psychiatric Medical Center, Osaka, Japan. usui@anat1.med.osaka-u.ac.jp., Doi M; Department of Neuroscience and Cell Biology, Graduate School of Medicine, The University of Osaka, Suita, Japan.; Addiction Research Unit, Osaka Psychiatric Research Center, Osaka Psychiatric Medical Center, Osaka, Japan., Shimada S; Department of Neuroscience and Cell Biology, Graduate School of Medicine, The University of Osaka, Suita, Japan.; United Graduate School of Child Development, The University of Osaka, Suita, Japan.; Global Center for Medical Engineering and Informatics, The University of Osaka, Suita, Japan.; Addiction Research Unit, Osaka Psychiatric Research Center, Osaka Psychiatric Medical Center, Osaka, Japan.
Source: Translational psychiatry [Transl Psychiatry] 2025 Oct 06; Vol. 15 (1), pp. 364. Date of Electronic Publication: 2025 Oct 06.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Electronic Cited Medium: Internet ISSN: 2158-3188 (Electronic) Linking ISSN: 21583188 NLM ISO Abbreviation: Transl Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2158-3188
DOI:10.1038/s41398-025-03613-y