Epigenetic modulation of VEGF-A/VEGFR2 pathway genes in OC/TME axis driving genetic upregulation and tumor plasticity.

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Title: Epigenetic modulation of VEGF-A/VEGFR2 pathway genes in OC/TME axis driving genetic upregulation and tumor plasticity.
Authors: Bhat A; Department of Immunology and Molecular Medicine, Sher-i-Kashmir Institute of Medical Sciences, Soura, Srinagar, Jammu & Kashmir, India., Bashir Y; Advanced Centre for Human Genetics, Sher-i-Kashmir Institute of Medical Sciences, Soura, Jammu & Kashmir, India., Baba AB; Advanced Centre for Human Genetics, Sher-i-Kashmir Institute of Medical Sciences, Soura, Jammu & Kashmir, India., Dar S; Advanced Centre for Human Genetics, Sher-i-Kashmir Institute of Medical Sciences, Soura, Jammu & Kashmir, India., Ahmad SZ; Department of Surgical Oncology, Sher-i-Kashmir Institute of Medical Sciences, Soura, Jammu & Kashmir, India., Yasin SB; Department of Pathology, Sher-i-Kashmir Institute of Medical Sciences, Soura, Jammu & Kashmir, India., Mir AW; Department of Surgical Oncology, Sher-i-Kashmir Institute of Medical Sciences, Soura, Jammu & Kashmir, India., Ahmad SN; Department of Medical Oncology, Sher-i-Kashmir Institute of Medical Sciences, Soura, Jammu & Kashmir, India., Yousuf T; Department of Immunology and Molecular Medicine, Sher-i-Kashmir Institute of Medical Sciences, Soura, Srinagar, Jammu & Kashmir, India., Afroze D; Department of Immunology and Molecular Medicine, Sher-i-Kashmir Institute of Medical Sciences, Soura, Srinagar, Jammu & Kashmir, India. afrozedil@gmail.com.; Advanced Centre for Human Genetics, Sher-i-Kashmir Institute of Medical Sciences, Soura, Jammu & Kashmir, India. afrozedil@gmail.com.
Source: Scientific reports [Sci Rep] 2025 Oct 07; Vol. 15 (1), pp. 34856. Date of Electronic Publication: 2025 Oct 07.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2045-2322
DOI:10.1038/s41598-025-04483-6