Study design and protocol of a randomized, pragmatic, comparative effectiveness trial evaluating a sequenced strategy for improving outcomes in people with knee osteoarthritis pain (SKOAP): Conservative treatment evaluation.

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Title: Study design and protocol of a randomized, pragmatic, comparative effectiveness trial evaluating a sequenced strategy for improving outcomes in people with knee osteoarthritis pain (SKOAP): Conservative treatment evaluation.
Authors: Allen HM; Johns Hopkins University, School of Medicine, Department of Psychiatry and Behavioral Sciences, 5510 Nathan Shock Drive, Ste 100, Baltimore, MD 21224, USA., Holena MM; Johns Hopkins University, School of Medicine, Department of Psychiatry and Behavioral Sciences, 5510 Nathan Shock Drive, Ste 100, Baltimore, MD 21224, USA., Allen LE; Johns Hopkins University, School of Public Health, Major Extremity Trauma Research Consortium, 415N. Washington Street, Baltimore, MD 21231, USA., Zhao S; Johns Hopkins University, School of Public Health, Major Extremity Trauma Research Consortium, 415N. Washington Street, Baltimore, MD 21231, USA., Castillo RC; Johns Hopkins University, School of Public Health, Major Extremity Trauma Research Consortium, 415N. Washington Street, Baltimore, MD 21231, USA., Cohen SP; Northwestern University Feinberg School of Medicine, Departments of Anesthesiology, Neurology, Physical Medicine & Rehabilitation, Psychiatry and Neurological Surgery, 259 E Erie St Ste 1400, Chicago, IL 60611, USA., Hurley RW; Wake Forest University School of Medicine, Departments of Anesthesiology, Translational Neuroscience, and Public Health; Pain Outcomes Lab; Medical Center Blvd, Winston-Salem, NC 27157, USA., Scharfstein DO; University of Utah, School of Medicine, Department of Population Health Sciences, Division of Biostatistics, 295 Chipeta Way, Salt Lake City, UT 84108, USA., Haythornthwaite JA; Johns Hopkins University, School of Medicine, Department of Psychiatry and Behavioral Sciences, 5510 Nathan Shock Drive, Ste 100, Baltimore, MD 21224, USA., Raja SN; Johns Hopkins University, School of Medicine, Department of Anesthesia and Critical Care Medicine, Division of Pain Medicine, 600N. Wolfe St., Baltimore, MD 21287, USA., Wegener ST; Johns Hopkins University School of Medicine, Department of Physical Medicine and Rehabilitation, 600N. Wolfe Street, Baltimore, MD 2128A7, USA., Rini CM; Northwestern University Feinberg School of Medicine, Department of Medical Social Science, 625N. Michigan Avenue, Chicago, IL 60611; Robert H. Lurie Comprehensive Cancer Center of Northwestern University; 675N St Clair St Fl 21 Ste 100, Chicago, IL 60611, USA., Keefe FJ; Duke University, School of Medicine, Departments of Psychiatry and Behavioral Sciences, Psychology and Neuroscience, Medicine, and Anesthesiology, 2200W Main St, Suite 340, Durham, NC 27705, USA., Bridges J; University of Utah, Utah Data Coordinating Center, 295 Chipeta Way, Salt Lake City, UT 84108, USA., Reeder R; University of Utah, School of Medicine, Department of Pediatrics, 295 Chipeta Way, Salt Lake City, UT 84108, USA., Thompson RE; Johns Hopkins University, School of Medicine, Johns Hopkins Institute for Clinical & Translational Research, Brian Injury Outcomes (BIOS), 750 E. Pratt St., 16th floor, Baltimore, MD 21202, USA., Hanley D; Johns Hopkins University, School of Medicine, Johns Hopkins Institute for Clinical & Translational Research, Brian Injury Outcomes (BIOS), 750 E. Pratt St., 16th floor, Baltimore, MD 21202, USA., Campbell CM; Johns Hopkins University, School of Medicine, Department of Psychiatry and Behavioral Sciences, 5510 Nathan Shock Drive, Ste 100, Baltimore, MD 21224, USA. Electronic address: ccampb41@jhmi.edu.
Corporate Authors: SKOAP Consortium
Source: Seminars in arthritis and rheumatism [Semin Arthritis Rheum] 2025 Dec; Vol. 75, pp. 152834. Date of Electronic Publication: 2025 Sep 23.
Publication Type: Journal Article; Clinical Trial Protocol
Journal Info: Publisher: W.B. Saunders Country of Publication: United States NLM ID: 1306053 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-866X (Electronic) Linking ISSN: 00490172 NLM ISO Abbreviation: Semin Arthritis Rheum Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1532-866X
DOI:10.1016/j.semarthrit.2025.152834