Analysis of myeloid neoplasms with isolated trisomy 19 reveals a novel MDS subgroup characterized by the presence of ring sideroblasts, fibrosis and SRSF2 and/or ASXL1 mutations.

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Title: Analysis of myeloid neoplasms with isolated trisomy 19 reveals a novel MDS subgroup characterized by the presence of ring sideroblasts, fibrosis and SRSF2 and/or ASXL1 mutations.
Authors: Hebeda KM; Department of Pathology, Radboud University Medical Center, Nijmegen, Netherlands. konnie.hebeda@radboudumc.nl., Boudová L; Department of Pathology, Medical Faculty, Charles University, Pilsen, Czech Republic.; Biopticka Laborator, Pilsen, Czech Republic., Corsten MF; Internal Medicine, Meander Medisch Centrum, Amersfoort, Netherlands., Ptáková N; Biopticka Laborator, Pilsen, Czech Republic.; Department of Biology and Medical Genetics, 2nd Faculty of Medicine, University Hospital Motol, Prague, Czech Republic., Haferlach T; Munich Leukemia Laboratory, Munich, Germany., de Graaf AO; Laboratory Hematology, Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, Netherlands., Cermak J; Institute of Hematology and Blood Transfusion, MDS Registry, Prague, Czech Republic., Vanecek T; Department of Pathology, Medical Faculty, Charles University, Pilsen, Czech Republic.; Biopticka Laborator, Pilsen, Czech Republic., Jansen JH; Laboratory Hematology, Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, Netherlands., Stevens-Kroef MJPL; Department of Human Genetics, Radboud University Medical Center, Nijmegen, Netherlands., Kroeze LI; Department of Pathology, Radboud University Medical Center, Nijmegen, Netherlands.
Source: Journal of hematopathology [J Hematop] 2025 Oct 09; Vol. 18 (1), pp. 45. Date of Electronic Publication: 2025 Oct 09.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Germany NLM ID: 101491976 Publication Model: Electronic Cited Medium: Internet ISSN: 1865-5785 (Electronic) Linking ISSN: 18655785 NLM ISO Abbreviation: J Hematop Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1865-5785
DOI:10.1007/s12308-025-00659-1