The relationship between urine output and time to methotrexate clearance in pediatric leukemia patients receiving high-dose methotrexate therapy.

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Title: The relationship between urine output and time to methotrexate clearance in pediatric leukemia patients receiving high-dose methotrexate therapy.
Authors: Wang YL; Divisions of Hematology/Oncology, Department of Pediatrics, Chang Gung Children's Hospital, Chang Gung University, 5 Fu-Shin Street, Kwei-Shan, Taoyuan, 333, Taiwan., Chang TY; Divisions of Hematology/Oncology, Department of Pediatrics, Chang Gung Children's Hospital, Chang Gung University, 5 Fu-Shin Street, Kwei-Shan, Taoyuan, 333, Taiwan., Chen SH; Divisions of Hematology/Oncology, Department of Pediatrics, Chang Gung Children's Hospital, Chang Gung University, 5 Fu-Shin Street, Kwei-Shan, Taoyuan, 333, Taiwan., Hsiao YW; Department of Nursing, Chang Gung Memorial Hospital, Taoyuan, Taiwan., Wen YC; Department of Nursing, Chang Gung Memorial Hospital, Taoyuan, Taiwan., Jaing TH; Divisions of Hematology/Oncology, Department of Pediatrics, Chang Gung Children's Hospital, Chang Gung University, 5 Fu-Shin Street, Kwei-Shan, Taoyuan, 333, Taiwan. jaing001@cgmh.org.tw.
Source: BMC cancer [BMC Cancer] 2025 Oct 09; Vol. 25 (1), pp. 1545. Date of Electronic Publication: 2025 Oct 09.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407 (Electronic) Linking ISSN: 14712407 NLM ISO Abbreviation: BMC Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1471-2407
DOI:10.1186/s12885-025-15064-1