HAND2 invades nucleolar condensates to pioneer lineage-specific cardiac pacemaker gene programs.
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| Title: | HAND2 invades nucleolar condensates to pioneer lineage-specific cardiac pacemaker gene programs. |
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| Authors: | Kulkarni K; Department of Internal Medicine, Cardiology Division, University of Texas Southwestern Medical Center, Dallas, TX, USA., Quinn G; Department of Immunology, University of Texas Southwestern Medical Center, Dallas, TX, USA., Dela Rosa J; Department of Internal Medicine, Cardiology Division, University of Texas Southwestern Medical Center, Dallas, TX, USA., Goetsch S; Department of Internal Medicine, Cardiology Division, University of Texas Southwestern Medical Center, Dallas, TX, USA., Pandit V; Department of Internal Medicine, Cardiology Division, University of Texas Southwestern Medical Center, Dallas, TX, USA., Wang L; Department of Internal Medicine, Cardiology Division, University of Texas Southwestern Medical Center, Dallas, TX, USA., Sakaguchi A; Department of Internal Medicine, Cardiology Division, University of Texas Southwestern Medical Center, Dallas, TX, USA., Sivakumar S; Department of Internal Medicine, Cardiology Division, University of Texas Southwestern Medical Center, Dallas, TX, USA., Munshi NV; Department of Internal Medicine, Cardiology Division, University of Texas Southwestern Medical Center, Dallas, TX, USA. Nikhil.Munshi@utsouthwestern.edu.; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA. Nikhil.Munshi@utsouthwestern.edu.; Hamon Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA. Nikhil.Munshi@utsouthwestern.edu.; McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, TX, USA. Nikhil.Munshi@utsouthwestern.edu.; Cecil H. and Ida Green Center for Reproductive Biology Sciences, University of Texas Southwestern Medical Center, Dallas, TX, USA. Nikhil.Munshi@utsouthwestern.edu. |
| Source: | Nature communications [Nat Commun] 2025 Oct 10; Vol. 16 (1), pp. 9024. Date of Electronic Publication: 2025 Oct 10. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-64076-9 |