The E3 ubiquitin ligase ZNRF3 restricts WNT receptor complex activity by stimulating the selective degradation of WNT-engaged FZD.
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| Title: | The E3 ubiquitin ligase ZNRF3 restricts WNT receptor complex activity by stimulating the selective degradation of WNT-engaged FZD. |
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| Authors: | Lu B; Discovery Sciences, Novartis Institutes for Biomedical Research, Cambridge, MA 02139, USA., Cong F; Discovery Sciences, Novartis Institutes for Biomedical Research, Cambridge, MA 02139, USA. |
| Source: | Science signaling [Sci Signal] 2025 Oct 14; Vol. 18 (908), pp. eadv1529. Date of Electronic Publication: 2025 Oct 14. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1937-9145 |
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| DOI: | 10.1126/scisignal.adv1529 |
