Gut microbiota-mediated berberine metabolism ameliorates cholestatic liver disease by suppressing 5-hydroxytryptamine production.

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Title: Gut microbiota-mediated berberine metabolism ameliorates cholestatic liver disease by suppressing 5-hydroxytryptamine production.
Authors: Tu D; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China., Lu C; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China., Guo J; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China., Chen Q; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China., Li X; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China., Wang Y; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China., Cheng L; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China., Jiang H; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China., Jian J; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China., Ge Y; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China., Hou Z; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China., Feng X; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China., Feng Y; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China., Zhou J; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China., Lei Y; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China., Diao H; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China., Ran L; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China., Zhou Y; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China., Xu Z; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China., Zhou J; 3National Drug Clinical Trial Institution, Xinqiao Hospital, Army Medical University, Chongqing, China., Tang B; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China., Yang S; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China.; Chongqing Institute for Brain and Intelligence, Guangyang Bay Laboratory, Chongqing, China.
Source: Clinical and molecular hepatology [Clin Mol Hepatol] 2026 Jan; Vol. 32 (1), pp. 221-238. Date of Electronic Publication: 2025 Oct 14.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Korean Association for the Study of the Liver Country of Publication: Korea (South) NLM ID: 101586730 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2287-285X (Electronic) Linking ISSN: 22872728 NLM ISO Abbreviation: Clin Mol Hepatol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Gut microbiota-mediated berberine metabolism ameliorates cholestatic liver disease by suppressing 5-hydroxytryptamine production.
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  Data: <searchLink fieldCode="AU" term="%22Tu+D%22">Tu D</searchLink>; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Lu+C%22">Lu C</searchLink>; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Guo+J%22">Guo J</searchLink>; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Chen+Q%22">Chen Q</searchLink>; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Cheng+L%22">Cheng L</searchLink>; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Jiang+H%22">Jiang H</searchLink>; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Jian+J%22">Jian J</searchLink>; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Ge+Y%22">Ge Y</searchLink>; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Hou+Z%22">Hou Z</searchLink>; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Feng+X%22">Feng X</searchLink>; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Feng+Y%22">Feng Y</searchLink>; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Zhou+J%22">Zhou J</searchLink>; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Lei+Y%22">Lei Y</searchLink>; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Diao+H%22">Diao H</searchLink>; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Ran+L%22">Ran L</searchLink>; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Zhou+Y%22">Zhou Y</searchLink>; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Xu+Z%22">Xu Z</searchLink>; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Zhou+J%22">Zhou J</searchLink>; 3National Drug Clinical Trial Institution, Xinqiao Hospital, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Tang+B%22">Tang B</searchLink>; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Yang+S%22">Yang S</searchLink>; Department of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing, China.; Chongqing Institute for Brain and Intelligence, Guangyang Bay Laboratory, Chongqing, China.
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  Data: <searchLink fieldCode="JN" term="%22101586730%22">Clinical and molecular hepatology</searchLink> [Clin Mol Hepatol] 2026 Jan; Vol. 32 (1), pp. 221-238. <i>Date of Electronic Publication: </i>2025 Oct 14.
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  Data: Journal Article; Randomized Controlled Trial
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Korean+Association+for+the+Study+of+the+Liver%22">Korean Association for the Study of the Liver </searchLink><i>Country of Publication: </i>Korea (South) <i>NLM ID: </i>101586730 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2287-285X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2222872728%22">22872728 </searchLink><i>NLM ISO Abbreviation: </i>Clin Mol Hepatol <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41087029
RecordInfo BibRecord:
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        Value: 10.3350/cmh.2025.0577
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        Text: English
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              Text: 2026 Jan
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