A prospective protocol for remotely investigating brain-behaviour-genetics associations in adolescent patients in a paediatric health system with pre-existing clinical brain MRIs.

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Title: A prospective protocol for remotely investigating brain-behaviour-genetics associations in adolescent patients in a paediatric health system with pre-existing clinical brain MRIs.
Authors: Mercedes L; The Department of Child and Adolescent Psychiatry and Behavioral Sciences, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; The Lifespan Brain Institute, The Children's Hospital of Philadelphia and Penn Medicine, Philadelphia, Pennsylvania, USA.; Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Buczek MJ; The Department of Child and Adolescent Psychiatry and Behavioral Sciences, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; The Lifespan Brain Institute, The Children's Hospital of Philadelphia and Penn Medicine, Philadelphia, Pennsylvania, USA.; Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Kafadar E; The Department of Child and Adolescent Psychiatry and Behavioral Sciences, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; The Lifespan Brain Institute, The Children's Hospital of Philadelphia and Penn Medicine, Philadelphia, Pennsylvania, USA.; Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, USA., DiDomenico G; The Department of Child and Adolescent Psychiatry and Behavioral Sciences, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; The Lifespan Brain Institute, The Children's Hospital of Philadelphia and Penn Medicine, Philadelphia, Pennsylvania, USA.; Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Jung B; The Department of Child and Adolescent Psychiatry and Behavioral Sciences, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; The Lifespan Brain Institute, The Children's Hospital of Philadelphia and Penn Medicine, Philadelphia, Pennsylvania, USA.; Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Zimmerman D; The Department of Child and Adolescent Psychiatry and Behavioral Sciences, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; The Lifespan Brain Institute, The Children's Hospital of Philadelphia and Penn Medicine, Philadelphia, Pennsylvania, USA.; Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Schabdach JM; The Department of Child and Adolescent Psychiatry and Behavioral Sciences, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; The Lifespan Brain Institute, The Children's Hospital of Philadelphia and Penn Medicine, Philadelphia, Pennsylvania, USA., Himes MM; The Department of Child and Adolescent Psychiatry and Behavioral Sciences, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; The Lifespan Brain Institute, The Children's Hospital of Philadelphia and Penn Medicine, Philadelphia, Pennsylvania, USA.; Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Sotardi S; Department of Radiology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Vossough A; Department of Radiology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Driesbaugh KH; Children's Hospital of Philadelphia Institutional Biobank, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Moore T; The Lifespan Brain Institute, The Children's Hospital of Philadelphia and Penn Medicine, Philadelphia, Pennsylvania, USA.; Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Barzilay R; The Department of Child and Adolescent Psychiatry and Behavioral Sciences, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; The Lifespan Brain Institute, The Children's Hospital of Philadelphia and Penn Medicine, Philadelphia, Pennsylvania, USA.; Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Calkins ME; The Department of Child and Adolescent Psychiatry and Behavioral Sciences, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Gur RE; The Department of Child and Adolescent Psychiatry and Behavioral Sciences, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; The Lifespan Brain Institute, The Children's Hospital of Philadelphia and Penn Medicine, Philadelphia, Pennsylvania, USA.; Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Roalf DR; The Department of Child and Adolescent Psychiatry and Behavioral Sciences, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; The Lifespan Brain Institute, The Children's Hospital of Philadelphia and Penn Medicine, Philadelphia, Pennsylvania, USA.; Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Satterthwaite TD; The Department of Child and Adolescent Psychiatry and Behavioral Sciences, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; The Lifespan Brain Institute, The Children's Hospital of Philadelphia and Penn Medicine, Philadelphia, Pennsylvania, USA.; Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Penn Lifespan Informatics and Neuroimaging Center, Philadelphia, Pennsylvania, USA., White LK; The Department of Child and Adolescent Psychiatry and Behavioral Sciences, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; The Lifespan Brain Institute, The Children's Hospital of Philadelphia and Penn Medicine, Philadelphia, Pennsylvania, USA.; Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Alexander-Bloch A; The Department of Child and Adolescent Psychiatry and Behavioral Sciences, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA aaron.alexander-bloch@pennmedicine.upenn.edu.; The Lifespan Brain Institute, The Children's Hospital of Philadelphia and Penn Medicine, Philadelphia, Pennsylvania, USA.; Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Source: BMJ open [BMJ Open] 2025 Oct 15; Vol. 15 (10), pp. e106431. Date of Electronic Publication: 2025 Oct 15.
Publication Type: Journal Article; Clinical Trial Protocol
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2044-6055
DOI:10.1136/bmjopen-2025-106431