Transcriptome and chromatin accessibility divergence during differentiation of a bipotential progenitor cell population to erythroblasts and megakaryocytes.

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Title: Transcriptome and chromatin accessibility divergence during differentiation of a bipotential progenitor cell population to erythroblasts and megakaryocytes.
Authors: Mishra T; The Pennsylvania State University, University Park, Pennsylvania, USA; Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania, USA. Electronic address: mtejas@stanford.edu., Giardine BM; The Pennsylvania State University, University Park, Pennsylvania, USA; Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania, USA., Morrissey CS; The Pennsylvania State University, University Park, Pennsylvania, USA; Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania, USA., Keller CA; The Pennsylvania State University, University Park, Pennsylvania, USA; Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania, USA., Heuston EF; National Human Genome Research institute, National Institutes of Health, Bethesda, Maryland, USA., Anderson SM; NHGRI Flow Cytometry Core Facility, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA., Paralkar VR; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Pimkin M; Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Weiss MJ; Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Bodine DM; National Human Genome Research institute, National Institutes of Health, Bethesda, Maryland, USA., Hardison RC; The Pennsylvania State University, University Park, Pennsylvania, USA; Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania, USA. Electronic address: rch8@psu.edu.
Source: The Journal of biological chemistry [J Biol Chem] 2025 Dec; Vol. 301 (12), pp. 110819. Date of Electronic Publication: 2025 Oct 14.
Publication Type: Journal Article; Research Support, N.I.H., Intramural
Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1083-351X
DOI:10.1016/j.jbc.2025.110819