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Dysfunction of Unc119, a Transducin-Binding Protein, Leads to Cone-Rod Dystrophy through Activating JAK-Stat and NF-κB Inflammatory Pathways in the Mouse Retina.

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Title: Dysfunction of Unc119, a Transducin-Binding Protein, Leads to Cone-Rod Dystrophy through Activating JAK-Stat and NF-κB Inflammatory Pathways in the Mouse Retina.
Authors: Kobayashi K; Laboratory for Molecular and Developmental Biology, Institute for Protein Research, The University of Osaka, Osaka 565-0871, Japan., Chaya T; Laboratory for Molecular and Developmental Biology, Institute for Protein Research, The University of Osaka, Osaka 565-0871, Japan., Tu HY; Laboratory for Molecular and Developmental Biology, Institute for Protein Research, The University of Osaka, Osaka 565-0871, Japan., Maeda Y; Laboratory for Molecular and Developmental Biology, Institute for Protein Research, The University of Osaka, Osaka 565-0871, Japan., Nakashima Y; Laboratory for Molecular and Developmental Biology, Institute for Protein Research, The University of Osaka, Osaka 565-0871, Japan., Tsutsumi R; Laboratory for Molecular and Developmental Biology, Institute for Protein Research, The University of Osaka, Osaka 565-0871, Japan., Yamamoto H; Laboratory for Molecular and Developmental Biology, Institute for Protein Research, The University of Osaka, Osaka 565-0871, Japan., Tsujii T; Laboratory for Molecular and Developmental Biology, Institute for Protein Research, The University of Osaka, Osaka 565-0871, Japan., Okuzaki D; Genome Information Research Center, Research Institute for Microbial Diseases, The University of Osaka, Osaka 565-0871, Japan., Furukawa T; Laboratory for Molecular and Developmental Biology, Institute for Protein Research, The University of Osaka, Osaka 565-0871, Japan takahisa.furukawa@protein.osaka-u.ac.jp.
Source: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2025 Nov 26; Vol. 45 (48). Date of Electronic Publication: 2025 Nov 26.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Electronic Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1529-2401
DOI:10.1523/JNEUROSCI.2245-24.2025