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Impact of drug-drug interaction of JAK inhibitors, CYP enzyme inhibitors and OAT3 inhibitors on persistence and infection rates in patients with autoimmune rheumatic diseases.

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Title: Impact of drug-drug interaction of JAK inhibitors, CYP enzyme inhibitors and OAT3 inhibitors on persistence and infection rates in patients with autoimmune rheumatic diseases.
Authors: Shao YJ; Graduate Institute of Biomedical Informatics, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan; Clinical Big Data Research Center, Taipei Medical University Hospital, Taipei, Taiwan; Health Data Analytics and Statistics Center, Office of Data Science, Taipei Medical University, Taipei, Taiwan., Kuo TT; Health Data Analytics and Statistics Center, Office of Data Science, Taipei Medical University, Taipei, Taiwan., Liao YJ; Department of Pharmacy, Taichung Veterans General Hospital, Taichung, Taiwan; Department of Pharmacy, National Yang-Ming Chiao Tung University, Taipei, Taiwan., Chen YT; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan., Chen IC; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan., Kao CM; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan; Division of Allergy, Immunology and Rheumatology, Taichung Veterans General Hospital, Taichung, Taiwan., Chen YJ; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan; Division of Allergy, Immunology and Rheumatology, Taichung Veterans General Hospital, Taichung, Taiwan., Chen YM; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan; Division of Allergy, Immunology and Rheumatology, Taichung Veterans General Hospital, Taichung, Taiwan; Graduate Institute of Clinical Medicine, College of Medicine, National Chung-Hsing University, Taichung, Taiwan; School of Medicine, National Yang-Ming Chiao Tung University, Taipei, Taiwan; Department of Post-Baccalaureate Medicine, College of Medicine, National Chung-Hsing University, Taichung, Taiwan; Precision Medicine Research Center, College of Medicine, National Chung-Hsing University, Taichung, Taiwan. Electronic address: ymchen1@vghtc.gov.tw.
Source: Joint bone spine [Joint Bone Spine] 2026 Mar; Vol. 93 (2), pp. 105990. Date of Electronic Publication: 2025 Oct 17.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Editions Elsevier Country of Publication: France NLM ID: 100938016 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1778-7254 (Electronic) Linking ISSN: 1297319X NLM ISO Abbreviation: Joint Bone Spine Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Impact of drug-drug interaction of JAK inhibitors, CYP enzyme inhibitors and OAT3 inhibitors on persistence and infection rates in patients with autoimmune rheumatic diseases.
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  Data: <searchLink fieldCode="AU" term="%22Shao+YJ%22">Shao YJ</searchLink>; Graduate Institute of Biomedical Informatics, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan; Clinical Big Data Research Center, Taipei Medical University Hospital, Taipei, Taiwan; Health Data Analytics and Statistics Center, Office of Data Science, Taipei Medical University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kuo+TT%22">Kuo TT</searchLink>; Health Data Analytics and Statistics Center, Office of Data Science, Taipei Medical University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liao+YJ%22">Liao YJ</searchLink>; Department of Pharmacy, Taichung Veterans General Hospital, Taichung, Taiwan; Department of Pharmacy, National Yang-Ming Chiao Tung University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+YT%22">Chen YT</searchLink>; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+IC%22">Chen IC</searchLink>; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kao+CM%22">Kao CM</searchLink>; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan; Division of Allergy, Immunology and Rheumatology, Taichung Veterans General Hospital, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+YJ%22">Chen YJ</searchLink>; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan; Division of Allergy, Immunology and Rheumatology, Taichung Veterans General Hospital, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+YM%22">Chen YM</searchLink>; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan; Division of Allergy, Immunology and Rheumatology, Taichung Veterans General Hospital, Taichung, Taiwan; Graduate Institute of Clinical Medicine, College of Medicine, National Chung-Hsing University, Taichung, Taiwan; School of Medicine, National Yang-Ming Chiao Tung University, Taipei, Taiwan; Department of Post-Baccalaureate Medicine, College of Medicine, National Chung-Hsing University, Taichung, Taiwan; Precision Medicine Research Center, College of Medicine, National Chung-Hsing University, Taichung, Taiwan. Electronic address: ymchen1@vghtc.gov.tw.
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  Data: <searchLink fieldCode="JN" term="%22100938016%22">Joint bone spine</searchLink> [Joint Bone Spine] 2026 Mar; Vol. 93 (2), pp. 105990. <i>Date of Electronic Publication: </i>2025 Oct 17.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Editions+Elsevier%22">Editions Elsevier </searchLink><i>Country of Publication: </i>France <i>NLM ID: </i>100938016 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1778-7254 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221297319X%22">1297319X </searchLink><i>NLM ISO Abbreviation: </i>Joint Bone Spine <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1016/j.jbspin.2025.105990
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      – Code: eng
        Text: English
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              Text: 2026 Mar
              Type: published
              Y: 2026
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