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Population Pharmacokinetic and Pharmacodynamic Modeling Analysis of rhIL-7-hyFc, a Hybrid Fc-Fused Long-Acting Interleukin-7, to Support Optimal Dosing Regimens in Patients with Solid Cancer.

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Title: Population Pharmacokinetic and Pharmacodynamic Modeling Analysis of rhIL-7-hyFc, a Hybrid Fc-Fused Long-Acting Interleukin-7, to Support Optimal Dosing Regimens in Patients with Solid Cancer.
Authors: Park S; Department of Clinical Pharmacology and Therapeutics, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Lee SM; Department of Clinical Pharmacology and Therapeutics, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Pak KC; Department of Clinical Pharmacology and Therapeutics, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Byun MS; Genexine, Inc., Seoul, Republic of Korea., Choi D; Neoimmunetech, Inc., Rockville, MD, USA., Lim HS; Department of Clinical Pharmacology and Therapeutics, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Source: Drug design, development and therapy [Drug Des Devel Ther] 2025 Oct 17; Vol. 19, pp. 9303-9320. Date of Electronic Publication: 2025 Oct 17 (Print Publication: 2025).
Publication Type: Journal Article; Clinical Trial, Phase I
Journal Info: Publisher: Dove Press Limited Country of Publication: New Zealand NLM ID: 101475745 Publication Model: eCollection Cited Medium: Internet ISSN: 1177-8881 (Electronic) Linking ISSN: 11778881 NLM ISO Abbreviation: Drug Des Devel Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1177-8881
DOI:10.2147/DDDT.S564085