Pan-modification profiling facilitates a cross-evolutionary dissection of the thermoregulated ribosomal epitranscriptome.

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Title: Pan-modification profiling facilitates a cross-evolutionary dissection of the thermoregulated ribosomal epitranscriptome.
Authors: Garcia-Campos MA; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel., Georgeson J; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel., Nir R; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel., Reichelt R; Institute of Microbiology & Archaea Centre, Single-Molecule Biochemistry Lab, Regensburg Center for Biochemistry (RCB), University of Regensburg, 93053 Regensburg, Germany., Fluke KA; Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523, USA., Matzov D; Department of Chemical and Structural Biology, Weizmann Institute of Science, Rehovot 7610001, Israel., Iyer V; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel., Burkhart BW; Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523, USA., Lui L; Molecular Ecosystems Biology Department, Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA., Kustanovich A; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel., Grünberger F; Institute of Microbiology & Archaea Centre, Single-Molecule Biochemistry Lab, Regensburg Center for Biochemistry (RCB), University of Regensburg, 93053 Regensburg, Germany., Thalalla-Gamage S; Chemical Biology Laboratory, National Cancer Institute, Frederick, MD, USA., Howpay-Manage SA; Chemical Biology Laboratory, National Cancer Institute, Frederick, MD, USA., Gerovac M; Faculty of Medicine, Institute for Molecular Infection Biology (IMIB), Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Centre for Infection Research (HZI), University of Würzburg, 97080 Würzburg, Germany., Alexandre N; Regensburg Centre for Biochemistry, Biochemistry III-Institute for Biochemistry, Genetics and Microbiology, University of Regensburg, Universitätsstraße 31, 93053 Regensburg, Germany., Nobe Y; Department of Chemistry, Graduate School of Science, Tokyo Metropolitan University, Hachioji-shi, Tokyo 192-0397, Japan., Nowak JS; Malopolska Centre of Biotechnology, Jagiellonian University, 30-387 Krakow, Poland., Perera M; Department of Chemistry and Health Research Institute, Michigan Technological University, 1400 Townsend Drive, Houghton, MI, USA., Apostle A; Department of Chemistry and Health Research Institute, Michigan Technological University, 1400 Townsend Drive, Houghton, MI, USA., Fang S; Department of Chemistry and Health Research Institute, Michigan Technological University, 1400 Townsend Drive, Houghton, MI, USA., Glatt S; Malopolska Centre of Biotechnology, Jagiellonian University, 30-387 Krakow, Poland; Department of Biological Sciences and Pathobiology, University of Veterinary Medicine Vienna, 1210 Vienna, Austria., Jona G; Bacteriology & Genomic Repository Unit, Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot 7610001, Israel., Ferreira-Cerca S; Regensburg Centre for Biochemistry, Biochemistry III-Institute for Biochemistry, Genetics and Microbiology, University of Regensburg, Universitätsstraße 31, 93053 Regensburg, Germany; Laboratoire de Biologie Structurale de la Cellule (BIOC), UMR 7654-CNRS, École polytechnique, Institut Polytechnique de Paris, Route de Saclay, 91128 Palaiseau, France., Vogel J; Faculty of Medicine, Institute for Molecular Infection Biology (IMIB), Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Centre for Infection Research (HZI), University of Würzburg, 97080 Würzburg, Germany., Taoka M; Department of Chemistry, Graduate School of Science, Tokyo Metropolitan University, Hachioji-shi, Tokyo 192-0397, Japan., Meier JL; Chemical Biology Laboratory, National Cancer Institute, Frederick, MD, USA., Westhof E; Architecture et Réactivité de l'ARN, Université de Strasbourg, Institut de biologie moléculaire et cellulaire du CNRS, Strasbourg 67084, France; Engineering Research Center of Clinical Functional Materials and Diagnosis & Treatment Devices of Zhejiang Province, Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou, China., Santangelo TJ; Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523, USA., Grohmann D; Institute of Microbiology & Archaea Centre, Single-Molecule Biochemistry Lab, Regensburg Center for Biochemistry (RCB), University of Regensburg, 93053 Regensburg, Germany., Shalev-Benami M; Department of Chemical and Structural Biology, Weizmann Institute of Science, Rehovot 7610001, Israel. Electronic address: moransb@weizmann.ac.il., Schwartz S; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel. Electronic address: schwartz@weizmann.ac.il.
Source: Cell [Cell] 2025 Nov 26; Vol. 188 (24), pp. 6825-6844.e28. Date of Electronic Publication: 2025 Oct 22.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1097-4172
DOI:10.1016/j.cell.2025.09.014