HCB101: a novel potent ligand-trap Fc-fusion protein targeting the CD47-SIRPα pathway with high safety and preclinical efficacy for hematological and solid tumors.
Saved in:
| Title: | HCB101: a novel potent ligand-trap Fc-fusion protein targeting the CD47-SIRPα pathway with high safety and preclinical efficacy for hematological and solid tumors. |
|---|---|
| Authors: | Wang JT; HanchorBio Inc, No. 1, Sec. 1, Tiding Blvd. Neihu Dist, Taipei City, 114066, Taiwan., Tseng CL; HanchorBio Inc, No. 1, Sec. 1, Tiding Blvd. Neihu Dist, Taipei City, 114066, Taiwan., Teng HF; HanchorBio Inc, No. 1, Sec. 1, Tiding Blvd. Neihu Dist, Taipei City, 114066, Taiwan., Kuo PH; HanchorBio Inc, No. 1, Sec. 1, Tiding Blvd. Neihu Dist, Taipei City, 114066, Taiwan., Cheng YC; HanchorBio Inc, No. 1, Sec. 1, Tiding Blvd. Neihu Dist, Taipei City, 114066, Taiwan., Chen YJ; HanchorBio Inc, No. 1, Sec. 1, Tiding Blvd. Neihu Dist, Taipei City, 114066, Taiwan., Lu YH; HanchorBio Inc, No. 1, Sec. 1, Tiding Blvd. Neihu Dist, Taipei City, 114066, Taiwan., Wang CC; HanchorBio Inc, No. 1, Sec. 1, Tiding Blvd. Neihu Dist, Taipei City, 114066, Taiwan., Shen TK; HanchorBio Inc, No. 1, Sec. 1, Tiding Blvd. Neihu Dist, Taipei City, 114066, Taiwan., Wang HF; HanchorBio Inc, No. 1, Sec. 1, Tiding Blvd. Neihu Dist, Taipei City, 114066, Taiwan., Tsai PL; HanchorBio Inc, No. 1, Sec. 1, Tiding Blvd. Neihu Dist, Taipei City, 114066, Taiwan., Wu YC; HanchorBio Inc, No. 1, Sec. 1, Tiding Blvd. Neihu Dist, Taipei City, 114066, Taiwan., Ho CH; HanchorBio Inc, No. 1, Sec. 1, Tiding Blvd. Neihu Dist, Taipei City, 114066, Taiwan., Sun WT; HanchorBio Inc, No. 1, Sec. 1, Tiding Blvd. Neihu Dist, Taipei City, 114066, Taiwan., Li YC; HanchorBio Inc, No. 1, Sec. 1, Tiding Blvd. Neihu Dist, Taipei City, 114066, Taiwan., Lee YH; HanchorBio Inc, No. 1, Sec. 1, Tiding Blvd. Neihu Dist, Taipei City, 114066, Taiwan., Hung YJ; HanchorBio Inc, No. 1, Sec. 1, Tiding Blvd. Neihu Dist, Taipei City, 114066, Taiwan., Chen M; Department of Pathology, UT Southwestern Medical Center, 2330 Inwood Rd, Dallas, 75390, TX, USA., Li Z; Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center - James, 460 W 10th Avenue, Columbus, 43210, OH, USA., Juo ZS; HanchorBio Inc, No. 1, Sec. 1, Tiding Blvd. Neihu Dist, Taipei City, 114066, Taiwan., Zhai W; HanchorBio Inc, No. 1, Sec. 1, Tiding Blvd. Neihu Dist, Taipei City, 114066, Taiwan. Wenwu_Zhai@hanchorbio.com., Liu SS; HanchorBio Inc, No. 1, Sec. 1, Tiding Blvd. Neihu Dist, Taipei City, 114066, Taiwan. Scott_Liu@hanchorbio.com. |
| Source: | Journal of hematology & oncology [J Hematol Oncol] 2025 Oct 23; Vol. 18 (1), pp. 87. Date of Electronic Publication: 2025 Oct 23. |
| Publication Type: | Letter |
| Journal Info: | Publisher: Biomed Central Country of Publication: England NLM ID: 101468937 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-8722 (Electronic) Linking ISSN: 17568722 NLM ISO Abbreviation: J Hematol Oncol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
|
Full text is not displayed to guests.
Login for full access.
|
|
| ISSN: | 1756-8722 |
|---|---|
| DOI: | 10.1186/s13045-025-01742-x |
