Mechanobiologically-optimized non-resorbable artificial bone for patient-matched scaffold-guided bone regeneration.
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| Title: | Mechanobiologically-optimized non-resorbable artificial bone for patient-matched scaffold-guided bone regeneration. |
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| Authors: | Clark JR; NHMRC Centre of Research Excellence for Applied Innovations in Oral Cancer, Camperdown, NSW, Australia. jonathan.clark@lh.org.au.; Integrated Prosthetics and Reconstruction, Chris O'Brien Lifehouse, Camperdown, NSW, Australia. jonathan.clark@lh.org.au.; Central Clinical School, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW, Australia. jonathan.clark@lh.org.au.; Royal Prince Alfred Institute of Academic Surgery, Sydney Local Health District, Camperdown, NSW, Australia. jonathan.clark@lh.org.au.; Department of Head and Neck Surgery, Sydney Head and Neck Cancer Institute, Chris O'Brien Lifehouse, Camperdown, NSW, Australia. jonathan.clark@lh.org.au., Al Maruf DSA; Integrated Prosthetics and Reconstruction, Chris O'Brien Lifehouse, Camperdown, NSW, Australia.; Central Clinical School, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW, Australia., Tomaskovic-Crook E; Arto Hardy Family Biomedical Innovation Hub, Chris O'Brien Lifehouse, Camperdown, NSW, Australia.; Intelligent Polymer Research Institute and Institute of Innovative Materials, Faculty of Engineering and Information Sciences, The University of Wollongong, Fairy Meadow, NSW, Australia.; School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW, Australia., Cheng K; Integrated Prosthetics and Reconstruction, Chris O'Brien Lifehouse, Camperdown, NSW, Australia.; Royal Prince Alfred Institute of Academic Surgery, Sydney Local Health District, Camperdown, NSW, Australia., Lewin WT; Arto Hardy Family Biomedical Innovation Hub, Chris O'Brien Lifehouse, Camperdown, NSW, Australia.; School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW, Australia.; Sarcoma and Surgical Research Centre, Chris O'Brien Lifehouse, Camperdown, NSW, Australia., Xin H; Integrated Prosthetics and Reconstruction, Chris O'Brien Lifehouse, Camperdown, NSW, Australia., Wan B; NHMRC Centre of Research Excellence for Applied Innovations in Oral Cancer, Camperdown, NSW, Australia.; School of Aerospace, Mechanical and Mechatronic Engineering, The University of Sydney, Camperdown, NSW, Australia., Ren J; NHMRC Centre of Research Excellence for Applied Innovations in Oral Cancer, Camperdown, NSW, Australia.; ARC Training Centre for Cells and Tissue Engineering Technologies, Central Analytical Research Facility, Research Infrastructure, Queensland University of Technology, Brisbane, QLD, Australia., Wu C; School of Aerospace, Mechanical and Mechatronic Engineering, The University of Sydney, Camperdown, NSW, Australia., Kruse HV; Arto Hardy Family Biomedical Innovation Hub, Chris O'Brien Lifehouse, Camperdown, NSW, Australia.; Sarcoma and Surgical Research Centre, Chris O'Brien Lifehouse, Camperdown, NSW, Australia.; School of Physics, The University of Sydney, Camperdown, NSW, Australia., Lawrence DK; Australian National Fabrication Facility-Materials Node, AIIM Facility, The University of Wollongong, Wollongong, NSW, Australia., Wise I; Laboratory Animal Services, The University of Sydney, Camperdown, NSW, Australia., Gupta A; NHMRC Centre of Research Excellence for Applied Innovations in Oral Cancer, Camperdown, NSW, Australia.; Integrated Prosthetics and Reconstruction, Chris O'Brien Lifehouse, Camperdown, NSW, Australia., Woodruff MA; NHMRC Centre of Research Excellence for Applied Innovations in Oral Cancer, Camperdown, NSW, Australia.; School of Mechanical, Medical and Process Engineering, Queensland University of Technology, Brisbane, QLD, Australia., Rad MA; Arto Hardy Family Biomedical Innovation Hub, Chris O'Brien Lifehouse, Camperdown, NSW, Australia.; School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW, Australia., Leinkram D; Integrated Prosthetics and Reconstruction, Chris O'Brien Lifehouse, Camperdown, NSW, Australia.; Central Clinical School, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW, Australia.; Department of Head and Neck Surgery, Sydney Head and Neck Cancer Institute, Chris O'Brien Lifehouse, Camperdown, NSW, Australia., Manzie T; NHMRC Centre of Research Excellence for Applied Innovations in Oral Cancer, Camperdown, NSW, Australia.; Integrated Prosthetics and Reconstruction, Chris O'Brien Lifehouse, Camperdown, NSW, Australia.; Central Clinical School, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW, Australia.; Department of Head and Neck Surgery, Sydney Head and Neck Cancer Institute, Chris O'Brien Lifehouse, Camperdown, NSW, Australia., Parthasarthi K; Integrated Prosthetics and Reconstruction, Chris O'Brien Lifehouse, Camperdown, NSW, Australia.; Central Clinical School, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW, Australia.; Department of Head and Neck Surgery, Sydney Head and Neck Cancer Institute, Chris O'Brien Lifehouse, Camperdown, NSW, Australia., Wykes J; Integrated Prosthetics and Reconstruction, Chris O'Brien Lifehouse, Camperdown, NSW, Australia.; Central Clinical School, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW, Australia.; Department of Head and Neck Surgery, Sydney Head and Neck Cancer Institute, Chris O'Brien Lifehouse, Camperdown, NSW, Australia., Low TH; Integrated Prosthetics and Reconstruction, Chris O'Brien Lifehouse, Camperdown, NSW, Australia.; Central Clinical School, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW, Australia.; Department of Otolaryngology - Head & Neck Surgery, Faculty of Medicine and Health Sciences, Macquarie University, Macquarie Park, NSW, Australia., Howes D; Integrated Prosthetics and Reconstruction, Chris O'Brien Lifehouse, Camperdown, NSW, Australia.; Sydney Dental School, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW, Australia., Froggatt C; Integrated Prosthetics and Reconstruction, Chris O'Brien Lifehouse, Camperdown, NSW, Australia.; Department of Head and Neck Surgery, Sydney Head and Neck Cancer Institute, Chris O'Brien Lifehouse, Camperdown, NSW, Australia., Gupta R; NHMRC Centre of Research Excellence for Applied Innovations in Oral Cancer, Camperdown, NSW, Australia.; Central Clinical School, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW, Australia.; Department of Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia., Wallace G; NHMRC Centre of Research Excellence for Applied Innovations in Oral Cancer, Camperdown, NSW, Australia.; Intelligent Polymer Research Institute and Institute of Innovative Materials, Faculty of Engineering and Information Sciences, The University of Wollongong, Fairy Meadow, NSW, Australia., Li Q; NHMRC Centre of Research Excellence for Applied Innovations in Oral Cancer, Camperdown, NSW, Australia.; School of Aerospace, Mechanical and Mechatronic Engineering, The University of Sydney, Camperdown, NSW, Australia.; Centre for Advanced Materials Technology, The University of Sydney, Darlington, NSW, Australia., McKenzie DR; Arto Hardy Family Biomedical Innovation Hub, Chris O'Brien Lifehouse, Camperdown, NSW, Australia.; Sarcoma and Surgical Research Centre, Chris O'Brien Lifehouse, Camperdown, NSW, Australia.; School of Physics, The University of Sydney, Camperdown, NSW, Australia., Crook JM; NHMRC Centre of Research Excellence for Applied Innovations in Oral Cancer, Camperdown, NSW, Australia. jeremy.crook@lh.org.au.; Arto Hardy Family Biomedical Innovation Hub, Chris O'Brien Lifehouse, Camperdown, NSW, Australia. jeremy.crook@lh.org.au.; Intelligent Polymer Research Institute and Institute of Innovative Materials, Faculty of Engineering and Information Sciences, The University of Wollongong, Fairy Meadow, NSW, Australia. jeremy.crook@lh.org.au.; School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW, Australia. jeremy.crook@lh.org.au.; Sarcoma and Surgical Research Centre, Chris O'Brien Lifehouse, Camperdown, NSW, Australia. jeremy.crook@lh.org.au. |
| Source: | Nature communications [Nat Commun] 2025 Oct 24; Vol. 16 (1), pp. 9422. Date of Electronic Publication: 2025 Oct 24. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-64466-z |
