Functional characterization of pathogenic SATB2 missense variants identifies distinct effects on chromatin binding and transcriptional activity.

Saved in:
Bibliographic Details
Title: Functional characterization of pathogenic SATB2 missense variants identifies distinct effects on chromatin binding and transcriptional activity.
Authors: den Hoed J; Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, the Netherlands., Semmekrot F; Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, the Netherlands., Verseput J; Department of Human Genetics, Radboudumc, Nijmegen, the Netherlands; Donders Institute for Brain, Cognition, and Behaviour, Radboud University, Nijmegen, the Netherlands., Dingemans AJM; Department of Human Genetics, Radboudumc, Nijmegen, the Netherlands; Donders Institute for Brain, Cognition, and Behaviour, Radboud University, Nijmegen, the Netherlands., Schijven D; Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, the Netherlands., Francks C; Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, the Netherlands; Donders Institute for Brain, Cognition, and Behaviour, Radboud University, Nijmegen, the Netherlands; Department of Medical Neuroscience, Radboud University Medical Center, Nijmegen, the Netherlands., Zarate YA; Section of Genetics and Metabolism, University of Arkansas for Medical Sciences, Little Rock, AR, USA; Division of Genetics and Metabolism, University of Kentucky, Lexington, KY, USA., Fisher SE; Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, the Netherlands; Donders Institute for Brain, Cognition, and Behaviour, Radboud University, Nijmegen, the Netherlands. Electronic address: simon.fisher@mpi.nl.
Source: HGG advances [HGG Adv] 2026 Jan 15; Vol. 7 (1), pp. 100537. Date of Electronic Publication: 2025 Oct 25.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101772885 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-2477 (Electronic) Linking ISSN: 26662477 NLM ISO Abbreviation: HGG Adv Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2666-2477
DOI:10.1016/j.xhgg.2025.100537