Protocol for a randomized controlled trial of steroid versus methotrexate as first-line monotherapy in the management of idiopathic granulomatous mastitis.

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Title: Protocol for a randomized controlled trial of steroid versus methotrexate as first-line monotherapy in the management of idiopathic granulomatous mastitis.
Authors: Goh SSN; Department of Surgery, National University Hospital and National University Health System, Singapore.; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore., Cheung P; Division of Rheumatology and Allergy, Department of Medicine, National University Hospital, Singapore., Tay SH; Division of Rheumatology and Allergy, Department of Medicine, National University Hospital, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Ma M; Division of Rheumatology and Allergy, Department of Medicine, National University Hospital, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Putti TC; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Tai BC; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore., Casida KK; Department of Surgery, National University Hospital and National University Health System, Singapore., Chua ZH; Department of General Surgery, National University Hospital, Singapore., Chew YJ; Department of General Surgery, National University Hospital, Singapore., Mohamed Riza NKB; Department of General Surgery, National University Hospital, Singapore., Liu J; Department of General Surgery, Ng Teng Fong General Hospital, Singapore., Hartman M; Department of Surgery, National University Hospital and National University Health System, Singapore.; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.
Source: PloS one [PLoS One] 2025 Oct 27; Vol. 20 (10), pp. e0333577. Date of Electronic Publication: 2025 Oct 27 (Print Publication: 2025).
Publication Type: Journal Article; Clinical Trial Protocol
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1932-6203
DOI:10.1371/journal.pone.0333577