DNA methylation patterns facilitate tracing the origin of neuroendocrine neoplasms.
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| Title: | DNA methylation patterns facilitate tracing the origin of neuroendocrine neoplasms. |
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| Authors: | Goeppert B; Institute of Pathology, Heidelberg University, Medical Faculty, University Hospital Heidelberg, Heidelberg, Germany. Benjamin.Goeppert@rkh-gesundheit.de.; Institute of Tissue Medicine and Pathology, University of Berne, Berne, Switzerland. Benjamin.Goeppert@rkh-gesundheit.de.; Institute of Pathology, RKH Hospital Ludwigsburg, Ludwigsburg, Germany. Benjamin.Goeppert@rkh-gesundheit.de., Charbel A; Institute of Pathology, Heidelberg University, Medical Faculty, University Hospital Heidelberg, Heidelberg, Germany.; Liver Cancer Center Heidelberg (LCCH), Heidelberg, Germany., Toth R; Luxembourg Institute of Health, Department of Cancer Research, Strassen, Luxembourg., Zhang Y; Luxembourg Institute of Health, Department of Cancer Research, Strassen, Luxembourg., Tabbakh D; Luxembourg Institute of Health, Department of Cancer Research, Strassen, Luxembourg., Albrecht T; Institute of Pathology, Heidelberg University, Medical Faculty, University Hospital Heidelberg, Heidelberg, Germany.; Liver Cancer Center Heidelberg (LCCH), Heidelberg, Germany., Schrimpf D; Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; German Consortium for Translational Cancer Research (DKTK), Heidelberg, Germany.; Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany., de Mestier L; Université Paris-Cité, Department of Pancreatology and Digestive Oncology, Beaujon Hospital (APHP) and INSERM U1149, Clichy, France., Cros J; Université Paris-Cité, Department of Pathology, Beaujon Hospital (APHP) and INSERM U1149, Clichy, France., Vogel MN; Diagnostic and Interventional Radiology, Thoraxklinik at University Hospital Heidelberg, Heidelberg, Germany.; Department of Radiology and Nuclear Medicine, Robert Bosch Hospital Stuttgart, Stuttgart, Germany., Chang DH; Liver Cancer Center Heidelberg (LCCH), Heidelberg, Germany.; Department of Diagnostic and Interventional Radiology, Heidelberg University Hospital, Heidelberg, Germany.; Department of Radiology and Nuclear Medicine, Luzerner Kantonsspital, University Teaching and Research Hospital, University of Lucerne, Lucerne, Switzerland., Bohn EM; Institute of Pathology, Heidelberg University, Medical Faculty, University Hospital Heidelberg, Heidelberg, Germany., Brobeil A; Institute of Pathology, Heidelberg University, Medical Faculty, University Hospital Heidelberg, Heidelberg, Germany.; Tissue Bank of the National Center for Tumor Diseases (NCT), Heidelberg, Germany., Ji J; The MOE Key Laboratory of Biosystems Homeostasis & Protection, Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, and Innovation Center for Cell Signaling Network, Life Sciences Institute, Zhejiang University, Hangzhou, China., Singer S; Institute of Pathology and Neuropathology, Eberhard-Karls University, Tuebingen, Germany., Nazarov PV; Luxembourg Institute of Health, Department of Cancer Research, Strassen, Luxembourg., Perren A; Institute of Tissue Medicine and Pathology, University of Berne, Berne, Switzerland., Apostolidis L; Liver Cancer Center Heidelberg (LCCH), Heidelberg, Germany.; National Center for Tumor Diseases (NCT) Heidelberg, Department of Medical Oncology, University Hospital Heidelberg, Heidelberg, Germany., von Deimling A; Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; German Consortium for Translational Cancer Research (DKTK), Heidelberg, Germany.; Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany., Roessler S; Institute of Pathology, Heidelberg University, Medical Faculty, University Hospital Heidelberg, Heidelberg, Germany. Stephanie.Roessler@med.uni-heidelberg.de.; Liver Cancer Center Heidelberg (LCCH), Heidelberg, Germany. Stephanie.Roessler@med.uni-heidelberg.de. |
| Source: | Nature communications [Nat Commun] 2025 Oct 27; Vol. 16 (1), pp. 9477. Date of Electronic Publication: 2025 Oct 27. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-65227-8 |
