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Rescue of imprinted genes by epigenome editing in human cellular models of Prader-Willi syndrome.

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Title: Rescue of imprinted genes by epigenome editing in human cellular models of Prader-Willi syndrome.
Authors: Nemoto A; Department of Physiology, Keio University School of Medicine, Tokyo, Japan.; Keio University Regenerative Medicine Research Center, Kawasaki, Japan.; Department of Pediatrics and Adolescent Medicine, Tokyo Medical University, Tokyo, Japan., Imaizumi K; Department of Physiology, Keio University School of Medicine, Tokyo, Japan.; Keio University Regenerative Medicine Research Center, Kawasaki, Japan.; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.; Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA, USA., Miya F; Center for Medical Genetics, Keio University School of Medicine, Tokyo, Japan., Hiroi Y; Department of Pediatrics and Adolescent Medicine, Tokyo Medical University, Tokyo, Japan., Yamada M; Center for Medical Genetics, Keio University School of Medicine, Tokyo, Japan., Ideno H; Department of Physiology, Keio University School of Medicine, Tokyo, Japan., Saitoh S; Department of Pediatrics and Neonatology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan., Kosaki K; Center for Medical Genetics, Keio University School of Medicine, Tokyo, Japan., Okuno H; Department of Physiology, Keio University School of Medicine, Tokyo, Japan. okuno.hironobu.6v@tokyo-med.ac.jp.; Keio University Regenerative Medicine Research Center, Kawasaki, Japan. okuno.hironobu.6v@tokyo-med.ac.jp.; Department of Pediatrics and Adolescent Medicine, Tokyo Medical University, Tokyo, Japan. okuno.hironobu.6v@tokyo-med.ac.jp.; Center for Medical Genetics, Keio University School of Medicine, Tokyo, Japan. okuno.hironobu.6v@tokyo-med.ac.jp., Okano H; Department of Physiology, Keio University School of Medicine, Tokyo, Japan. hidokano@keio.jp.; Keio University Regenerative Medicine Research Center, Kawasaki, Japan. hidokano@keio.jp.
Source: Nature communications [Nat Commun] 2025 Oct 28; Vol. 16 (1), pp. 9442. Date of Electronic Publication: 2025 Oct 28.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Rescue of imprinted genes by epigenome editing in human cellular models of Prader-Willi syndrome.
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  Data: <searchLink fieldCode="AU" term="%22Nemoto+A%22">Nemoto A</searchLink>; Department of Physiology, Keio University School of Medicine, Tokyo, Japan.; Keio University Regenerative Medicine Research Center, Kawasaki, Japan.; Department of Pediatrics and Adolescent Medicine, Tokyo Medical University, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Imaizumi+K%22">Imaizumi K</searchLink>; Department of Physiology, Keio University School of Medicine, Tokyo, Japan.; Keio University Regenerative Medicine Research Center, Kawasaki, Japan.; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.; Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Miya+F%22">Miya F</searchLink>; Center for Medical Genetics, Keio University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Hiroi+Y%22">Hiroi Y</searchLink>; Department of Pediatrics and Adolescent Medicine, Tokyo Medical University, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Yamada+M%22">Yamada M</searchLink>; Center for Medical Genetics, Keio University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Ideno+H%22">Ideno H</searchLink>; Department of Physiology, Keio University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Saitoh+S%22">Saitoh S</searchLink>; Department of Pediatrics and Neonatology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Kosaki+K%22">Kosaki K</searchLink>; Center for Medical Genetics, Keio University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Okuno+H%22">Okuno H</searchLink>; Department of Physiology, Keio University School of Medicine, Tokyo, Japan. okuno.hironobu.6v@tokyo-med.ac.jp.; Keio University Regenerative Medicine Research Center, Kawasaki, Japan. okuno.hironobu.6v@tokyo-med.ac.jp.; Department of Pediatrics and Adolescent Medicine, Tokyo Medical University, Tokyo, Japan. okuno.hironobu.6v@tokyo-med.ac.jp.; Center for Medical Genetics, Keio University School of Medicine, Tokyo, Japan. okuno.hironobu.6v@tokyo-med.ac.jp.<br /><searchLink fieldCode="AU" term="%22Okano+H%22">Okano H</searchLink>; Department of Physiology, Keio University School of Medicine, Tokyo, Japan. hidokano@keio.jp.; Keio University Regenerative Medicine Research Center, Kawasaki, Japan. hidokano@keio.jp.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Oct 28; Vol. 16 (1), pp. 9442. <i>Date of Electronic Publication: </i>2025 Oct 28.
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              Text: 2025 Oct 28
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