HIF2α inhibits glutaminase clustering in mitochondria to sustain growth of clear cell renal cell carcinoma.

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Bibliographic Details
Title: HIF2α inhibits glutaminase clustering in mitochondria to sustain growth of clear cell renal cell carcinoma.
Authors: Zhao W; Department of Medicine, Cardiovascular Institute, and Institute of Diabetes Obesity and Metabolism, and., Demczyszyn SM; The Abramson Family Cancer Research Institute, Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Coffey NJ; The Abramson Family Cancer Research Institute, Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Jiang Y; The Abramson Family Cancer Research Institute, Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Kim B; McAllister Heart Institute, School of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA., Bowers S; McAllister Heart Institute, School of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA., Bowman C; Biology Department, Williams College, Williamstown, Massachusetts, USA., Noji MC; The Abramson Family Cancer Research Institute, Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Jang C; Department of Biological Chemistry, School of Medicine, University of California, Irvine, California, USA., Simon MC; The Abramson Family Cancer Research Institute, Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Arany Z; Department of Medicine, Cardiovascular Institute, and Institute of Diabetes Obesity and Metabolism, and., Kim B; Department of Pathology and Laboratory Medicine, McAllister Heart Institute, Nutrition Obesity Research Center, and Lineberger Cancer Center, University of North Carolina, Chapel Hill, North Carolina, USA.
Source: JCI insight [JCI Insight] 2025 Oct 30; Vol. 10 (23). Date of Electronic Publication: 2025 Oct 30 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: eCollection Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2379-3708
DOI:10.1172/jci.insight.182711